TY - JOUR
T1 - Confocal Microscopy in Skin Cancer
AU - Ahlgrimm-Siess, Verena
AU - Laimer, Martin
AU - Rabinovitz, Harold S.
AU - Oliviero, Margaret
AU - Hofmann-Wellenhof, Rainer
AU - Marghoob, Ashfaq A.
AU - Scope, Alon
N1 - Publisher Copyright:
© 2018, The Author(s).
PY - 2018/6/1
Y1 - 2018/6/1
N2 - Purpose of Review: Reflectance confocal microscopy (RCM) enables imaging of skin lesions at cellular level resolution at the bedside (in vivo) or in freshly excised tissue (ex vivo). This article provides an overview of strengths and limitations of non-invasive RCM in skin cancer diagnosis. Recent Findings: RCM features of common melanocytic and non-melanocytic skin neoplasms such as melanoma, actinic keratosis/squamous cell carcinoma, basal cell carcinoma, and nevi have been well defined and show good correlation with dermoscopic and histopathologic findings. Due to its technical properties, RCM is especially suitable for the examination of flat skin lesions. Summary: In vivo RCM has been shown to increase the accuracy of non-invasive diagnosis of common skin neoplasms and is a valuable adjunct to dermoscopy, particularly in cosmetically and functionally sensitive areas such as the face or the genital area.
AB - Purpose of Review: Reflectance confocal microscopy (RCM) enables imaging of skin lesions at cellular level resolution at the bedside (in vivo) or in freshly excised tissue (ex vivo). This article provides an overview of strengths and limitations of non-invasive RCM in skin cancer diagnosis. Recent Findings: RCM features of common melanocytic and non-melanocytic skin neoplasms such as melanoma, actinic keratosis/squamous cell carcinoma, basal cell carcinoma, and nevi have been well defined and show good correlation with dermoscopic and histopathologic findings. Due to its technical properties, RCM is especially suitable for the examination of flat skin lesions. Summary: In vivo RCM has been shown to increase the accuracy of non-invasive diagnosis of common skin neoplasms and is a valuable adjunct to dermoscopy, particularly in cosmetically and functionally sensitive areas such as the face or the genital area.
KW - Basal cell carcinoma
KW - Dermoscopy
KW - Facial macules
KW - Histopathology
KW - Lentigo maligna
KW - Melanoma
KW - Nevi
KW - Non-melanoma skin cancer
KW - Reflectance confocal microscopy
KW - Skin tumors
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U2 - 10.1007/s13671-018-0218-9
DO - 10.1007/s13671-018-0218-9
M3 - Review article
AN - SCOPUS:85051196083
SN - 2162-4933
VL - 7
SP - 105
EP - 118
JO - Current Dermatology Reports
JF - Current Dermatology Reports
IS - 2
ER -