@inbook{dd891cd911ba4602868ffb531a49c9e0,
title = "Control of ENaC-mediated sodium reabsorption in the distal nephron by Bradykinin",
abstract = "Kinins, such as Bradykinin (BK), are peptide hormones of the kallikrein-kinin system. Apart from being a vasodilator, BK also increases urinary sodium excretion to reduce systemic blood pressure. It is becoming appreciated that BK modulates function of the epithelial Na+ channel in the distal part of the renal nephron to affect tubular sodium reabsorption. In this chapter, we outline the molecular details, as well as discuss the physiological relevance of this regulation for the whole organism sodium homeostasis and setting chronic blood pressure.",
keywords = "ACE inhibition, Blood pressure, Kidney, Natriuresis, Renal tubule, Salt sensitivity",
author = "Mykola Mamenko and Oleg Zaika and Nabila Boukelmoune and Eric Madden and Oleh Pochynyuk",
note = "Funding Information: This research was supported by NIH-NIDDK DK095029 (to O. P.), AHA-GIA-13GRNT16220002 (to O. P.), and 14POST20380979 (to M. M.). Publisher Copyright: {\textcopyright} 2015 Elsevier Inc.",
year = "2015",
doi = "10.1016/bs.vh.2014.12.005",
language = "English (US)",
series = "Vitamins and Hormones",
publisher = "Academic Press Inc.",
pages = "137--154",
booktitle = "Vitamins and Hormones",
address = "United States",
}