Coping and the course of mother's depressive symptoms during and after pediatric bone marrow transplantation

Sharon Manne, Katherine DuHamel, Jamie Ostroff, Susan Parsons, D. Richard Martini, Sharon E. Williams, Laura Mee, Sandra Griffin Bishop Sexson, Jane Austin, Gary Winkel, Farid Boulad, William H. Redd

Research output: Contribution to journalArticlepeer-review

34 Scopus citations


Objective: To evaluate the role of maternal coping strategies in depressive symptoms experienced by mothers of children undergoing bone marrow transplantation (BMT). Method: A total of 207 mothers completed measures of coping and depressive symptoms at the time of the child's BMT, 3 and 6 months post-BMT. The sample was collected between 1998 and 2002. The acceptance rate was 73%.The contribution of demographic, illness and treatment parameters, and mothers' concerns about the child were also evaluated. Growth curve modeling was used to evaluate the role of coping in the course of depressive symptoms. Both main effects and interactions of coping strategies with time of assessment were evaluated. Results: Acceptance and humor were associated with reductions in maternal depressive symptoms, and planning and alcohol/substance use were associated with increases in maternal depressive symptoms. Positive reframing, use of emotional support, and use of religion were associated with the course of depressive symptoms, but the magnitude of associations differed depending on the use of the coping strategies at the time of transplantation. Mothers' fears about the child also predicted depressive symptoms. Conclusions: Acceptance and humor may be targets for behavioral interventions to reduce mothers' depressive symptoms during and after pediatric BMT hospitalization.

Original languageEnglish (US)
Pages (from-to)1055-1068
Number of pages14
JournalJournal of the American Academy of Child and Adolescent Psychiatry
Issue number9
StatePublished - Sep 2003
Externally publishedYes


  • Coping
  • Maternal adjustment
  • Pediatric bone marrow transplantation
  • Psychological distress

ASJC Scopus subject areas

  • Developmental and Educational Psychology
  • Psychiatry and Mental health


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