Abstract
The effects of early life adversity can be observed across the lifespan, and the hypothalamic-pituitary-adrenal (HPA) and hypothalamic-pituitary-gonadal (HPG) axes could be mechanistic intermediaries underlying this phenomenon. The current study examined 50 adolescent males aged 12-18 in a maximum-security correctional and treatment setting. Saliva samples were collected five times a day for 2 days and assayed for cortisol, testosterone, and DHEA. Youth completed semi-structured life stress interviews and self-reports of child maltreatment to index adversity. When youth had higher testosterone levels, they had higher cortisol and DHEA levels, indicating positive "coupling" of the HPA-HPG axes. In addition, children experiencing greater life adversity had tighter coupling of the HPA-HPG axes. Additional analyses hint that coupling may be driven largely by HPG axis functioning. Results indicate that positive coupling of the HPA-HPG axis is observed within incarcerated adolescents, especially for those with the greatest life stress.
Original language | English (US) |
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Pages (from-to) | 705-718 |
Number of pages | 14 |
Journal | Developmental Psychobiology |
Volume | 57 |
Issue number | 6 |
DOIs | |
State | Published - Sep 1 2015 |
Keywords
- Adolescence
- Cortisol
- DHEA
- Dual-axis
- HLM
- HPA
- HPG
- Stress
- Testosterone
ASJC Scopus subject areas
- Developmental and Educational Psychology
- Developmental Neuroscience
- Developmental Biology
- Behavioral Neuroscience