Current understanding on antihepatocarcinoma effects of xiao Chai Hu Tang and its constituents

Ningning Zheng, Jianye Dai, Huijuan Cao, Shujun Sun, Junwei Fang, Qianhua Li, Shibing Su, Yongyu Zhang, Mingfeng Qiu, Shuang Huang

Research output: Contribution to journalReview articlepeer-review

28 Scopus citations


Xiao Chai Hu Tang (XCHT), a compound formula originally recorded in an ancient Chinese medical book Shanghanlun, has been used to treat chronic liver diseases for a long period of time in China. Although extensive studies have been demonstrated the efficacy of this formula to treat chronic hepatitis, hepatic fibrosis, and hepatocarcinoma, how it works against these diseases still awaits full understanding. Here, we firstly present an overview arranging from the entire formula to mechanism studies of single herb in XCHT and their active components, from a new perspective of "separation study," and we tried our best to both detailedly and systematically organize the antihepatocarcinoma effects of it, hoping that the review will facilitate the strive on elucidating how XCHT elicits its antihepatocarcinoma role.

Original languageEnglish (US)
Article number529458
JournalEvidence-based Complementary and Alternative Medicine
StatePublished - 2013
Externally publishedYes

ASJC Scopus subject areas

  • Complementary and alternative medicine


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