CYP4F enzymes are the major enzymes in human liver microsomes that catalyze the O-demethylation of the antiparasitic prodrug DB289 [2,5-bis(4- amidinophenyl)furan-bis-O-methylamidoxime]

  • Michael Zhuo Wang
  • , Janelle Y. Saulter
  • , Etsuko Usuki
  • , Yen Ling Cheung
  • , Michael Hall
  • , Arlene S. Bridges
  • , Greg Loewen
  • , Oliver T. Parkinson
  • , Chad E. Stephens
  • , James L. Allen
  • , Darryl C. Zeldin
  • , David W. Boykin
  • , Richard R. Tidwell
  • , Andrew Parkinson
  • , Mary F. Paine
  • , James Edwin Hall

    Research output: Contribution to journal › Article › peer-review

    87 Scopus citations

    Fingerprint

    Dive into the research topics of 'CYP4F enzymes are the major enzymes in human liver microsomes that catalyze the O-demethylation of the antiparasitic prodrug DB289 [2,5-bis(4- amidinophenyl)furan-bis-O-methylamidoxime]'. Together they form a unique fingerprint.

    Keyphrases

    Pharmacology, Toxicology and Pharmaceutical Science