Abstract
Synovial fluid from 20 patients with rheumatoid arthritis was analyzed to detect human cytomegalovirus (CMV) genomic material using polymerase chain reaction. Of 20 samples tested, 9 were positive for CMV by either ethidium bromide staining or Southern blotting. In contrast, CMV was detected in only 2 of 18 control patients with osteoarthritis. These results suggest an etiologic relationship between CMV and rheumatoid arthritis.
Original language | English (US) |
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Pages (from-to) | 161-164 |
Number of pages | 4 |
Journal | Clinical and Experimental Rheumatology |
Volume | 10 |
Issue number | 2 |
State | Published - 1992 |
Externally published | Yes |
ASJC Scopus subject areas
- Immunology and Allergy
- Rheumatology
- Immunology