Delayed sexual development: A study of 252 patients

Richard H. Reindollar, J. Rogers Byrd, Paul G. McDonough

Research output: Contribution to journalArticlepeer-review

144 Scopus citations


A series of 252 patients with abnormalities of pubertal development are reported. Ovarian failure, followed by Rokitansky syndrome and then physiologic delay, are the most frequently encountered etiologies. Other etiologies are diverse and numericaily less frequent. The average age of presentation, patient's height, somatic anomalies, diagnostic errors, and subsequent reproductive potential of each diagnostic group are reported. Only 35 (14%) of all patients presenting with abnormalities of pubertal development had subsequent normal reproductive potential. All of these patients were in the physiologic delay category.

Original languageEnglish (US)
Pages (from-to)371-380
Number of pages10
JournalAmerican journal of obstetrics and gynecology
Issue number4
StatePublished - Jun 15 1981
Externally publishedYes

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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