Dermoscopy of acral melanoma: A multicenter study on behalf of the international dermoscopy society

Ralph P. Braun, L. Thomas, S. W. Dusza, O. Gaide, S. Menzies, S. Dalle, A. Blum, G. Argenziano, I. Zalaudek, A. Kopf, H. Rabinovitz, M. Oliviero, A. Perrinaud, H. Cabo, M. Pizzichetta, L. Pozo, D. Langford, M. Tanaka, T. Saida, A. M. Perusquia OrtizJ. Kreusch, V. De Giorgi, D. Piccolo, J. M. Grichnik, H. Kittler, S. Puig, J. Malvehy, S. Seidenari, I. Stanganelli, L. French, A. A. Marghoob

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


Background: Most studies on dermoscopy of acral lesions were conducted in Asian populations. In this study, we analyzed these features in a predominantly Caucasian population. Objective: Estimate the prevalence of dermoscopic features in acral lesions, and assess their level of agreement between observers. Methods: In this retrospective multicenter study, 167 acral lesions (66 melanomas) were evaluated for 13 dermoscopic patterns by 26 physicians, via a secured Internet platform. Results: Parallel furrow pattern, bizarre pattern, and diffuse pigmentation with variable shades of brown had the highest prevalence. The agreement for lesion patterns between physicians was variable. Agreement was dependent on the level of diagnostic difficulty. Conclusion: Lesions with a diameter >1 cm were more likely to be melanoma. We found as well that a benign pattern can be seen in parts of melanomas. For this reason one should evaluate an acral lesion for the presence of malignant patterns first.

Original languageEnglish (US)
Pages (from-to)373-380
Number of pages8
Issue number4
StatePublished - Jan 2014
Externally publishedYes


  • Acral melanoma
  • Caucasian population
  • Dermoscopy

ASJC Scopus subject areas

  • Dermatology


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