TY - JOUR
T1 - Diagnosis of recurrent uterine carcinosarcoma by fine-needle aspiration cytology
T2 - Report of a case
AU - Shidham, Vinod
AU - Gupta, Dilip
AU - Galindo, Lorenzo M.
AU - Haber, Marian
AU - Grotkowski, Carolyn
AU - Edmonds, Pamela
AU - Subichin, Steven J.
AU - George, Varghese
AU - England, James
PY - 2000
Y1 - 2000
N2 - Uterine carcinosarcomas are uncommon, aggressive neoplasms usually afflicting postmenopausal women. Histologically, they are characterized by the presence of both malignant epithelial and stromal cells. The latter may be either homologous or heterologous in nature. The cytologic diagnosis of carcinosarcoma via fine-needle aspiration (FNA) was previously described for primary tumors arising in the parotid gland, breast, lung, and ovary. Although the diagnosis of uterine carcinosarcoma via cervicovaginal, endometrial, and peritoneal fluid cytology has been described, the FNA cytology diagnosis of recurrent uterine carcinosarcoma has only been rarely described. We present a case of recurrent uterine carcinosarcoma in a 59-yr-old woman, diagnosed by ultrasound-guided FNA cytology. Cytologic smears showed a biphasic neoplasm consisting of both malignant columnar epithelial and spindle cells, in a background of tumor diathesis. This case illustrates the diagnostic utility of aspiration cytology in the investigation of recurrent carcinosarcoma in clinically suspicious lesions arising postsurgery. (C) 2000 Wiley-Liss, Inc.
AB - Uterine carcinosarcomas are uncommon, aggressive neoplasms usually afflicting postmenopausal women. Histologically, they are characterized by the presence of both malignant epithelial and stromal cells. The latter may be either homologous or heterologous in nature. The cytologic diagnosis of carcinosarcoma via fine-needle aspiration (FNA) was previously described for primary tumors arising in the parotid gland, breast, lung, and ovary. Although the diagnosis of uterine carcinosarcoma via cervicovaginal, endometrial, and peritoneal fluid cytology has been described, the FNA cytology diagnosis of recurrent uterine carcinosarcoma has only been rarely described. We present a case of recurrent uterine carcinosarcoma in a 59-yr-old woman, diagnosed by ultrasound-guided FNA cytology. Cytologic smears showed a biphasic neoplasm consisting of both malignant columnar epithelial and spindle cells, in a background of tumor diathesis. This case illustrates the diagnostic utility of aspiration cytology in the investigation of recurrent carcinosarcoma in clinically suspicious lesions arising postsurgery. (C) 2000 Wiley-Liss, Inc.
KW - Carcinosarcoma
KW - Cytology
KW - Fine-needle aspiration
KW - Malignant mixed Mullerian tumor
KW - Uterus
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U2 - 10.1002/1097-0339(200008)23:2<108::AID-DC9>3.0.CO;2-O
DO - 10.1002/1097-0339(200008)23:2<108::AID-DC9>3.0.CO;2-O
M3 - Article
C2 - 10888756
AN - SCOPUS:0033867237
SN - 8755-1039
VL - 23
SP - 108
EP - 113
JO - Diagnostic Cytopathology
JF - Diagnostic Cytopathology
IS - 2
ER -