Diagnosis of recurrent uterine carcinosarcoma by fine-needle aspiration cytology: Report of a case

Vinod Shidham, Dilip Gupta, Lorenzo M. Galindo, Marian Haber, Carolyn Grotkowski, Pamela Edmonds, Steven J. Subichin, Varghese George, James England

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Uterine carcinosarcomas are uncommon, aggressive neoplasms usually afflicting postmenopausal women. Histologically, they are characterized by the presence of both malignant epithelial and stromal cells. The latter may be either homologous or heterologous in nature. The cytologic diagnosis of carcinosarcoma via fine-needle aspiration (FNA) was previously described for primary tumors arising in the parotid gland, breast, lung, and ovary. Although the diagnosis of uterine carcinosarcoma via cervicovaginal, endometrial, and peritoneal fluid cytology has been described, the FNA cytology diagnosis of recurrent uterine carcinosarcoma has only been rarely described. We present a case of recurrent uterine carcinosarcoma in a 59-yr-old woman, diagnosed by ultrasound-guided FNA cytology. Cytologic smears showed a biphasic neoplasm consisting of both malignant columnar epithelial and spindle cells, in a background of tumor diathesis. This case illustrates the diagnostic utility of aspiration cytology in the investigation of recurrent carcinosarcoma in clinically suspicious lesions arising postsurgery. (C) 2000 Wiley-Liss, Inc.

Original languageEnglish (US)
Pages (from-to)108-113
Number of pages6
JournalDiagnostic Cytopathology
Issue number2
StatePublished - 2000
Externally publishedYes


  • Carcinosarcoma
  • Cytology
  • Fine-needle aspiration
  • Malignant mixed Mullerian tumor
  • Uterus

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology


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