Diagnostic utility of wireless motility capsule in gastrointestinal dysmotility

Satish S.C. Rao, Krupa Mysore, Ashok Attaluri, Jessica Valestin

Research output: Contribution to journalArticlepeer-review

50 Scopus citations


Goals: To examine the diagnostic utility of wireless motility capsule (WMC) in patients with suspected gastrointestinal (GI) dysmotility. Background: Subjects with suspected GI motility disorders undergo invasive and expensive diagnostic tests. In these patients, whether WMC provides clinically useful information is unknown. Study: Patients with symptoms of dysmotility and normal endoscopic/radiologic evaluations were assessed with WMC test and conventional motility tests (CMT). Diagnostic utility of WMC was assessed retrospectively by examining device agreement and new information compared with CMT. Results: On the basis of predominant symptom(s), 86 patients were classified into 2 subgroups: lower GI (LGI=50) and upper GI (UGI=36). Clinical suspicion was confirmed in 52% and 66% of patients, respectively, and there was good device agreement between WMC and CMT in 76% and 81% in the LGI and UGI groups, respectively. There was new diagnostic information with the WMC test in 53% of the LGI (P=0.006) and 47% of the UGI group (P=0.001). WMC detected generalized motility disorder in 44 (51%) patients and influenced management in 30% of LGI and 50% of UGI subjects. Conclusions: WMC confirmed clinical suspicion, provided new diagnostic information, influenced clinical management, and detected many patients with generalized motility disorder. It had good device agreement with conventional tests.

Original languageEnglish (US)
Pages (from-to)684-690
Number of pages7
JournalJournal of Clinical Gastroenterology
Issue number8
StatePublished - Sep 2011
Externally publishedYes


  • colonic transit
  • constipation
  • gastric emptying
  • gastroparesis
  • wireless motility capsule

ASJC Scopus subject areas

  • Gastroenterology


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