Differentiation of benign from malignant breast masses by time-intensity evaluation of contrast enhanced MRI

Fred W. Flickinger; Jerry David Allison; Richard M. Sherry; John C. Wright

doi:10.1016/0730-725X(93)90002-U

Differentiation of benign from malignant breast masses by time-intensity evaluation of contrast enhanced MRI

Fred W. Flickinger, Jerry David Allison, Richard M. Sherry, John C. Wright

Research output: Contribution to journal › Article › peer-review

149 Scopus citations

Abstract

Using gadolinium-DTPA enhanced MRI we analyzed the enhancement characteristics of palpable breast masses in 23 patients-10 cancers and 13 benign lesions. The most specific finding for separating benign from malignant lesions was a ratio of maximum intensity change divided by the time interval during which this first occurred. Designated ranges of this ratio were specific for benign disease and sensitive for malignancy in this small patient group. Three of eight fibroadenomas exhibited enhancement patterns indistinguishable from cancer.

Original language	English (US)
Pages (from-to)	617-620
Number of pages	4
Journal	Magnetic Resonance Imaging
Volume	11
Issue number	5
DOIs	https://doi.org/10.1016/0730-725X(93)90002-U
State	Published - Jan 1 1993

Keywords

Breast neoplasms, diagnosis
Gadolinium-DTPA
Magnetic resonance (MR), contrast enhancement

ASJC Scopus subject areas

Biophysics
Biomedical Engineering
Radiology Nuclear Medicine and imaging

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/0730-725X(93)90002-U

Cite this

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title = "Differentiation of benign from malignant breast masses by time-intensity evaluation of contrast enhanced MRI",

abstract = "Using gadolinium-DTPA enhanced MRI we analyzed the enhancement characteristics of palpable breast masses in 23 patients-10 cancers and 13 benign lesions. The most specific finding for separating benign from malignant lesions was a ratio of maximum intensity change divided by the time interval during which this first occurred. Designated ranges of this ratio were specific for benign disease and sensitive for malignancy in this small patient group. Three of eight fibroadenomas exhibited enhancement patterns indistinguishable from cancer.",

keywords = "Breast neoplasms, diagnosis, Gadolinium-DTPA, Magnetic resonance (MR), contrast enhancement",

author = "Flickinger, {Fred W.} and Allison, {Jerry David} and Sherry, {Richard M.} and Wright, {John C.}",

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T1 - Differentiation of benign from malignant breast masses by time-intensity evaluation of contrast enhanced MRI

AU - Flickinger, Fred W.

AU - Allison, Jerry David

AU - Sherry, Richard M.

AU - Wright, John C.

PY - 1993/1/1

Y1 - 1993/1/1

N2 - Using gadolinium-DTPA enhanced MRI we analyzed the enhancement characteristics of palpable breast masses in 23 patients-10 cancers and 13 benign lesions. The most specific finding for separating benign from malignant lesions was a ratio of maximum intensity change divided by the time interval during which this first occurred. Designated ranges of this ratio were specific for benign disease and sensitive for malignancy in this small patient group. Three of eight fibroadenomas exhibited enhancement patterns indistinguishable from cancer.

AB - Using gadolinium-DTPA enhanced MRI we analyzed the enhancement characteristics of palpable breast masses in 23 patients-10 cancers and 13 benign lesions. The most specific finding for separating benign from malignant lesions was a ratio of maximum intensity change divided by the time interval during which this first occurred. Designated ranges of this ratio were specific for benign disease and sensitive for malignancy in this small patient group. Three of eight fibroadenomas exhibited enhancement patterns indistinguishable from cancer.

KW - Breast neoplasms, diagnosis

KW - Gadolinium-DTPA

KW - Magnetic resonance (MR), contrast enhancement

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JO - Magnetic Resonance Imaging

JF - Magnetic Resonance Imaging

IS - 5

ER -

Differentiation of benign from malignant breast masses by time-intensity evaluation of contrast enhanced MRI

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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