Abstract
Summary: DNA-BAR is a software package for selecting DNA probes (henceforth referred to as distinguishers) that can be used in genomic-based identification of microorganisms. Given the genomic sequences of the microorganisms, DNA-BAR finds a near-minimum number of distinguishers yielding a distinct hybridization pattern for each microorganism. Selected distinguishers satisfy user specified bounds on length, melting temperature and GC content, as well as redundancy and cross-hybridization constraints.
Original language | English (US) |
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Pages (from-to) | 3424-3426 |
Number of pages | 3 |
Journal | Bioinformatics |
Volume | 21 |
Issue number | 16 |
DOIs | |
State | Published - Aug 15 2005 |
Externally published | Yes |
ASJC Scopus subject areas
- Statistics and Probability
- Biochemistry
- Molecular Biology
- Computer Science Applications
- Computational Theory and Mathematics
- Computational Mathematics