E11/Podoplanin Protein Stabilization Through Inhibition of the Proteasome Promotes Osteocyte Differentiation in Murine in Vitro Models

Keyphrases

• Bone Homeostasis 25%
• Bortezomib 50%
• Calpain Inhibitor 50%
• Co-immunoprecipitation (co-IP) 25%
• Dendrite Formation 75%
• Dose Effect 25%
• Downstream Signaling 25%
• Exogenous Treatment 25%
• Functional Mechanism 25%
• Future Therapeutics 25%
• IDG-SW3 25%
• Immunoblotting 25%
• In Vitro Model 100%
• Lactacystin 25%
• Matrix Mineralization 25%
• Mechanistic Understanding 25%
• Membrane Glycoproteins 25%
• MG132 50%
• MLO-A5 100%
• MRNA Expression 25%
• MRNA Level 25%
• Osteoblast 50%
• Osteoblast Cells 25%
• Osteocyte 50%
• Osteogenic Differentiation 100%
• Podoplanin 100%
• Post-translational 25%
• Primary Osteoblasts 25%
• Protease Inhibitors 75%
• Protein Level 75%
• Protein Stabilization 100%
• Regulatory Mechanism 25%
• RhoA 50%
• Selective Inhibitor 25%
• Small GTPase 25%
• Therapeutic Approaches 25%
• Withaferin A 25%

Biochemistry, Genetics and Molecular Biology

• Calpastatin 66%
• Glycoprotein 33%
• Homeostasis 33%
• Immunoprecipitation 33%
• Messenger RNA 66%
• MG132 66%
• Mineralization 33%
• Osteoblast 100%
• Osteocyte 100%
• Proteasome 100%
• Proteasome Inhibitor 100%
• Small GTPase 33%
• Transfection 33%
• Western Blot 33%
• Withaferin A 33%

Immunology and Microbiology

• Cell Line 16%
• Genetic Transfection 16%
• Glycoprotein 16%
• Homeostasis 16%
• Immunoprecipitation 16%
• Mineralization 16%
• Osteoblast 50%
• Osteocyte 100%
• Proteasome 100%
• Western Blot 16%