@article{bf4708ade30b43d0a645ea7041f0ba86,
title = "Early-onset respiratory failure caused by severe congenital neuromuscular disease",
abstract = "Two unrelated infants with low Apgar scores, pneumothoraces, and severe pulmonary hypertension were treated with extracorporeal membrane oxygenation while receiving chemical sedation and neuromuscular paralysis. After decannulation from extracorporeal membrane oxygenation, hypotonia and hypoventilation persisted. Neurologic evaluation confirmed that both infants had a congenital myopathy.",
author = "Sandler, {D. L.} and Burchfield, {D. J.} and McCarthy, {J. A.} and Rojiani, {A. M.} and Drummond, {W. H.}",
note = "Funding Information: The infant arrived with hypotonia and minimal spontaneous activity, receiving fentanyl and pancuronium. A radiograph of the Supported in part by grants 92CG1A/7 and 92GIA/858 from the American Heart Association, Florida Affiliate. Submitted for publication Sept. 28, 1993; accepted Dec. 29, 1993. Reprint requests: W. H. Drummond, MD, Department of Pediatrics, Box 100296 JHMHC, Gainesville, FL 32610. Copyright | 1994 by Mosby-Year Book, Inc. 0022-3476/94/$3.00 + 0 9/24/53900 chest showed resolving pneumothoraces, clear lung fields, and thin ribs (Fig. 1, A). When the infant's respiratory failure worsened, he was treated with ECMO for 6 days without complications. Hypotonia persisted after discontinuation of sedation. At age 12 days, extubation failed because of atelectasis and hypoventilation. Computed tomography of the head showed mild cerebral atrophy, and focal slowing was present on an electroencephalogram.",
year = "1994",
month = apr,
doi = "10.1016/S0022-3476(05)83148-8",
language = "English (US)",
volume = "124",
pages = "636--638",
journal = "The Journal of Pediatrics",
issn = "0022-3476",
publisher = "Mosby Inc.",
number = "4",
}