TY - JOUR
T1 - Effect of oral estrogen on substrate utilization in postmenopausal women
AU - Lwin, Rebecca
AU - Darnell, Betty
AU - Oster, Robert
AU - Lawrence, Jeannine
AU - Foster, Jill
AU - Azziz, Ricardo
AU - Gower, Barbara A.
PY - 2008/10
Y1 - 2008/10
N2 - We tested the hypothesis that a 2-month intervention with unopposed oral conjugated equine estrogens (0.625 mg/d) would decrease lipid oxidation, as assessed by 24-hour, whole-room, indirect calorimetry in 14 postmenopausal women. Estrogen (E) treatment was associated with declines in both 24-hour and postprandial lipid oxidation and an increase in fat mass (mean [±SD] 2-month difference 1.1 ± 1.0 kg; mean 6-month difference 1.8 ± 2.2 kg), suggesting that, on an acute basis, oral E may increase adiposity by limiting lipid oxidation.
AB - We tested the hypothesis that a 2-month intervention with unopposed oral conjugated equine estrogens (0.625 mg/d) would decrease lipid oxidation, as assessed by 24-hour, whole-room, indirect calorimetry in 14 postmenopausal women. Estrogen (E) treatment was associated with declines in both 24-hour and postprandial lipid oxidation and an increase in fat mass (mean [±SD] 2-month difference 1.1 ± 1.0 kg; mean 6-month difference 1.8 ± 2.2 kg), suggesting that, on an acute basis, oral E may increase adiposity by limiting lipid oxidation.
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U2 - 10.1016/j.fertnstert.2007.07.1317
DO - 10.1016/j.fertnstert.2007.07.1317
M3 - Article
C2 - 18001731
AN - SCOPUS:52949146046
SN - 0015-0282
VL - 90
SP - 1275
EP - 1278
JO - Fertility and sterility
JF - Fertility and sterility
IS - 4
ER -