Effect of prosthetic mitral valve geometry and orientation on flow dynamics in a model human left ventricle

K. B. Chandran; R. Schoephoerster; K. C. Dellsperger

doi:10.1016/0021-9290(89)90184-X

Effect of prosthetic mitral valve geometry and orientation on flow dynamics in a model human left ventricle

K. B. Chandran, R. Schoephoerster, K. C. Dellsperger

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

Abstract

Pulsatile flow dynamics through bileaflet (St Jude and Duromedics), tilting disc (Bjork-Shiley and Omniscience), caged ball (Starr-Edwards), pericardial (Edwards) and porcine (Carpentier-Edwards) mitral valves in a model human left ventricle (LV) were studied. The model human ventricle, obtained from an in situ diastolic casting, was incorporated into a mock circulatory system. Measurements were made at various heart rates and flow rates. These included the transvalvular pressure drop and regurgitation in percent and cm³ beat^-1. The effect of valve geometry and the orientation of the valve with respect to the valve annulus was analyzed using a flow visualization technique. Qualitative flow visualization study indicates certain preferred orientations for the tilting disc and bileaflet valve prostheses in order to obtain a smooth washout of flow in the LV chamber.

Original language	English (US)
Pages (from-to)	51-57,59-65
Journal	Journal of Biomechanics
Volume	22
Issue number	1
DOIs	https://doi.org/10.1016/0021-9290(89)90184-X
State	Published - 1989
Externally published	Yes

ASJC Scopus subject areas

Biophysics
Rehabilitation
Biomedical Engineering
Orthopedics and Sports Medicine

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10.1016/0021-9290(89)90184-X

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@article{61df76136b104d7ebba879d7cd678dfc,

title = "Effect of prosthetic mitral valve geometry and orientation on flow dynamics in a model human left ventricle",

abstract = "Pulsatile flow dynamics through bileaflet (St Jude and Duromedics), tilting disc (Bjork-Shiley and Omniscience), caged ball (Starr-Edwards), pericardial (Edwards) and porcine (Carpentier-Edwards) mitral valves in a model human left ventricle (LV) were studied. The model human ventricle, obtained from an in situ diastolic casting, was incorporated into a mock circulatory system. Measurements were made at various heart rates and flow rates. These included the transvalvular pressure drop and regurgitation in percent and cm3 beat-1. The effect of valve geometry and the orientation of the valve with respect to the valve annulus was analyzed using a flow visualization technique. Qualitative flow visualization study indicates certain preferred orientations for the tilting disc and bileaflet valve prostheses in order to obtain a smooth washout of flow in the LV chamber.",

author = "Chandran, {K. B.} and R. Schoephoerster and Dellsperger, {K. C.}",

note = "Funding Information: Acknowledgements-Thpea rtial support of this work by grantsf rom the AmericanH eart AssociationI,o wa Affiliate (85-G-S and 87-G-8) is gratefully acknowledged.D r Dellspergerw as supportedb y a National ResearchS ervice Award from the NIH (lF32HL 07347) durintgh e courseo f this work. The following valve manufacturerksi ndly provided us with the valves used in this study: American Edwards (Starr-Edwards, Carpentier-Edwardsa nd Ed-wardsP ericardial)H; emexS cientific( Duromedics)M; edical Inc. (OmniscienceS);h iley Inc. (Bjork-Shiley);a nd St Jude Medical,I nc. (St Jude).",

year = "1989",

doi = "10.1016/0021-9290(89)90184-X",

language = "English (US)",

volume = "22",

pages = "51--57,59--65",

journal = "Journal of Biomechanics",

issn = "0021-9290",

publisher = "Elsevier Limited",

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TY - JOUR

T1 - Effect of prosthetic mitral valve geometry and orientation on flow dynamics in a model human left ventricle

AU - Chandran, K. B.

AU - Schoephoerster, R.

AU - Dellsperger, K. C.

N1 - Funding Information: Acknowledgements-Thpea rtial support of this work by grantsf rom the AmericanH eart AssociationI,o wa Affiliate (85-G-S and 87-G-8) is gratefully acknowledged.D r Dellspergerw as supportedb y a National ResearchS ervice Award from the NIH (lF32HL 07347) durintgh e courseo f this work. The following valve manufacturerksi ndly provided us with the valves used in this study: American Edwards (Starr-Edwards, Carpentier-Edwardsa nd Ed-wardsP ericardial)H; emexS cientific( Duromedics)M; edical Inc. (OmniscienceS);h iley Inc. (Bjork-Shiley);a nd St Jude Medical,I nc. (St Jude).

PY - 1989

Y1 - 1989

N2 - Pulsatile flow dynamics through bileaflet (St Jude and Duromedics), tilting disc (Bjork-Shiley and Omniscience), caged ball (Starr-Edwards), pericardial (Edwards) and porcine (Carpentier-Edwards) mitral valves in a model human left ventricle (LV) were studied. The model human ventricle, obtained from an in situ diastolic casting, was incorporated into a mock circulatory system. Measurements were made at various heart rates and flow rates. These included the transvalvular pressure drop and regurgitation in percent and cm3 beat-1. The effect of valve geometry and the orientation of the valve with respect to the valve annulus was analyzed using a flow visualization technique. Qualitative flow visualization study indicates certain preferred orientations for the tilting disc and bileaflet valve prostheses in order to obtain a smooth washout of flow in the LV chamber.

AB - Pulsatile flow dynamics through bileaflet (St Jude and Duromedics), tilting disc (Bjork-Shiley and Omniscience), caged ball (Starr-Edwards), pericardial (Edwards) and porcine (Carpentier-Edwards) mitral valves in a model human left ventricle (LV) were studied. The model human ventricle, obtained from an in situ diastolic casting, was incorporated into a mock circulatory system. Measurements were made at various heart rates and flow rates. These included the transvalvular pressure drop and regurgitation in percent and cm3 beat-1. The effect of valve geometry and the orientation of the valve with respect to the valve annulus was analyzed using a flow visualization technique. Qualitative flow visualization study indicates certain preferred orientations for the tilting disc and bileaflet valve prostheses in order to obtain a smooth washout of flow in the LV chamber.

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Effect of prosthetic mitral valve geometry and orientation on flow dynamics in a model human left ventricle

Abstract

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