Effect of R3487/MEM3454, a novel nicotinic α7 receptor partial agonist and 5-HT3 antagonist on sustained attention in rats

Keyphrases

• 5-HT3 Antagonist 100%
• 5-HT3 Receptor 25%
• Accuracy Performance 75%
• Acetylcholinesterase Inhibitors (AChEI) 25%
• Adult Female 25%
• Attention Task 50%
• Attentional Processes 25%
• Correct Rejection 50%
• Dependent Tests 25%
• Different Pretreatment 25%
• Dose Effect 25%
• Galanthamine 100%
• Hit Accuracy 75%
• Partial Agonist 100%
• Positive Modulator 25%
• Rejection Performance 50%
• Signal Detection Task 25%
• Sprague-Dawley Rats 25%
• Sustained Attention 100%
• Therapeutic Potential 25%
• Time Effect 25%
• Visual Signals 25%

Neuroscience

• 5-HT3 Antagonist 100%
• Acetylcholinesterase Inhibitor 25%
• Galantamine 100%
• Positive Allosteric Modulator 25%
• Receptor Partial Agonist 100%
• Serotonin 3 Receptor 25%