Effects of denture base resins on oral epithelial cells

Carol A. Lefebvre, George S. Sclluster, Gretchen B. Caughman, W. Frank Caughman

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


The current proliferation of light-polymerized denture base resins and the continual modification of their formutations make standardized biocompatibility testing a necessity. The biocompatibilities of three light-polymerized denture base resins were compared using an in vitro epithelial cell culture system. The effect of varied lengths of polymerization of denture base resin on cell toxicity was examined. This study indicated that light-polymerized denture base resins have an effect on oral epithelial cells that appears to be related to the specific formulation of the material and not to the type of polymerization required. Varying the polymerization time or light-polymerization unit appeared to have little effect.

Original languageEnglish (US)
Pages (from-to)371-376
Number of pages6
JournalInternational Journal of Prosthodontics
Issue number4
StatePublished - 1991

ASJC Scopus subject areas

  • General Medicine


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