Abstract
Dentine permeability measurements were made each hour for 6 h in tooth cavities prepared in control dogs or dogs which had been pretreated with a purified fraction of snake venom to deplete their plasma of fibrinogen. The control dogs exhibited a progressive fall in dentine permeability (~ 50 per cent reduction in 6 h); the permeability in the fibrinogen-depleted dogs only fell 15 per cent in 6 h. The results implicate plasma proteins, particularly high molecular-weight proteins such as fibrinogen, as agents which reduce dentine permeability in vivo.
Original language | English (US) |
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Pages (from-to) | 725-728 |
Number of pages | 4 |
Journal | Archives of Oral Biology |
Volume | 29 |
Issue number | 9 |
DOIs | |
State | Published - 1984 |
ASJC Scopus subject areas
- Otorhinolaryngology
- General Dentistry
- Cell Biology