Effects of gold laser on the avian chorioallantoic membrane

Catherine J. Rees, Jacqueline Allen, Gregory N. Postma, Peter C. Belafsky

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Objectives: Office-based lasers have revolutionized the treatment of laryngeal disease. The 980-nm Gold laser is a device that may offer some practical advantages over other office lasers. The chick chorioallantoic membrane has been proposed as a model for predicting the effects of photoangiolytic lasers on vocal fold microvasculature. We sought to evaluate the effects of the Gold laser in this model. Methods: Vascular reactions in first-order vessels were determined for the Gold laser with both 0° straight and 30° angled laser fibers. Vessels were treated at 15 W and a 500-ms pulse interval, with a 1-mm working distance. Pulse widths of 300 ms and 500 ms were evaluated. All vessels were treated until selective coagulation or vessel rupture. Results: We performed 60 trials on 30 embryos. The mean energy delivered was 33.7 J for the straight fiber and 51.2 J for the angled fiber. The laser achieved selective vessel coagulation without rupture in 100% (30 of 30) of straight fiber trials and in 100% (30 of 30) of angled fiber trials. In 6.7% (2 of 30) of straight fiber and 10% (3 of 30) of angled fiber trials, it caused minor injury to the surrounding albumin as indicated by white coagulum outside the vessel. Conclusions: The Gold laser effectively coagulates small vessels without rupture at a working distance of 1 mm and settings of 15 W, 500-ms pulse interval, and 300- to 500-ms pulse width.

Original languageEnglish (US)
Pages (from-to)50-53
Number of pages4
JournalAnnals of Otology, Rhinology and Laryngology
Issue number1
StatePublished - Jan 2010


  • Chorioallantoic membrane
  • Gold laser
  • Larynx
  • Laser
  • Phonosurgery
  • Vocal fold

ASJC Scopus subject areas

  • Otorhinolaryngology


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