@article{420b3e8f62ed4a6d9148349c5bd398c8,
title = "Effects of methylphenidate on cardiovascular responses in attention deficit hyperactivity disordered adolescents",
abstract = "The short-term dose effects of methylphenidate were examined on cardiovascular measures in 11 black male adolescents diagnosed as having attention deficit hyperactivity disorder (ADHD). In a double-blind, crossover design with randomized order, the subjects received placebo and each of three methylphenidate doses (0.15, 0.3, and 0.5 mg/kg) for a period of 2 weeks per medication dosage. Significant main effects were found for diastolic and systolic blood pressure; however, pairwise comparisons revealed a significant linear increase in diastolic blood pressure only. Because of the unexpected increase in diastolic blood pressure, careful monitoring of black adolescents who are receiving methylphenidate is recommended.",
keywords = "Attention deficit hyperactivity disorder Blood pressure Methylphenidate",
author = "Brown, {Ronald T.} and Sexson, {Sandra B.}",
note = "Funding Information: This project was supportedi n part by BRSG SO7 RR05364 awardedb y{\textquoteright}the Biomedical Research Support Grant Program, Division of ResearcljR esourcesN, ational Instituteso f Health, and by an awivd from the Emory University researchfu nd. Julia McMichael,M .D., and the residentsa t the PediatricA p pointmentC linic at GradyH ospitala ssistedin refe&ng patients for this study, and Ann Abramowitz,P h.D., madem anyu seful SU&Stions Concerningth e preparationo f this paper. Funding Information: Medical management of pri ed 1972; 287960-6. 29. ystolic arterial hypertension. I Medicine for Practicing physicians. Boston, 8utterworth Pub-lications, 1983. This project was supported in part by BRSG SO7 awarded by the Biomedical Research Support Grant Props, Divisioti of Research Resources, National Institutes of Health and by an award the Emory Lktiversity research fund. Julia McMicha .D., and the residents at the Pediatric Appointment Clinic at Grady Hospital assisted in referring patients for this study, and Ann Abramowitz, Ph.D., made many useful suggestions concerning the preparation of this paper.",
year = "1989",
month = may,
doi = "10.1016/0197-0070(89)90229-5",
language = "English (US)",
volume = "10",
pages = "179--183",
journal = "Journal of Adolescent Health Care",
issn = "0197-0070",
publisher = "Elsevier USA",
number = "3",
}
