Efficacy and safety results from ASCEMBL, a multicenter, open-label, phase 3 study of asciminib, a first-in-class STAMP inhibitor, vs bosutinib (BOS) in patients (Pts) with chronic myeloid leukemia in chronic phase (CML-CP) previously treated with ≥2 tyrosine kinase inhibitors (TKIs)

Andreas Hochhaus; Carla Boquimpani; Delphine Rea; Yosuke Minami; Elza Lomaia; Sergey Voloshin; Anna G. Turkina; Dong Wook Kim; Jane Apperley; Jorge E. Cortes; Andre Abdo; Laura Maria Fogliatto; Dennis Dong Hwan Kim; Philipp D. le Coutre; Susanne Saussele; Mario Annunziata; Timothy P. Hughes; Naeem A. Chaudhri; Lynette C.Y. Chee; Valentín García Gutiérrez; Koji Sasaki; Paola Aimone; Alex Allepuz; Sarah Quenet; Véronique Bédoucha; Michael J. Mauro

doi:10.1182/BLOOD-2020-143816

Efficacy and safety results from ASCEMBL, a multicenter, open-label, phase 3 study of asciminib, a first-in-class STAMP inhibitor, vs bosutinib (BOS) in patients (Pts) with chronic myeloid leukemia in chronic phase (CML-CP) previously treated with ≥2 tyrosine kinase inhibitors (TKIs)

Andreas Hochhaus, Carla Boquimpani, Delphine Rea, Yosuke Minami, Elza Lomaia, Sergey Voloshin, Anna G. Turkina, Dong Wook Kim, Jane Apperley, Jorge E. Cortes, Andre Abdo, Laura Maria Fogliatto, Dennis Dong Hwan Kim, Philipp D. le Coutre, Susanne Saussele, Mario Annunziata, Timothy P. Hughes, Naeem A. Chaudhri, Lynette C.Y. Chee, Valentín García GutiérrezKoji Sasaki, Paola Aimone, Alex Allepuz, Sarah Quenet, Véronique Bédoucha, Michael J. Mauro

Medicine

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19 Scopus citations

Original language	English (US)
Journal	Blood
Volume	136
DOIs	https://doi.org/10.1182/BLOOD-2020-143816
State	Published - Nov 19 2020

ASJC Scopus subject areas

Biochemistry
Immunology
Hematology
Cell Biology

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Hochhaus, A., Boquimpani, C., Rea, D., Minami, Y., Lomaia, E., Voloshin, S., Turkina, A. G., Kim, D. W., Apperley, J., Cortes, J. E., Abdo, A., Fogliatto, L. M., Kim, D. D. H., le Coutre, P. D., Saussele, S., Annunziata, M., Hughes, T. P., Chaudhri, N. A., Chee, L. C. Y., ... Mauro, M. J. (2020). Efficacy and safety results from ASCEMBL, a multicenter, open-label, phase 3 study of asciminib, a first-in-class STAMP inhibitor, vs bosutinib (BOS) in patients (Pts) with chronic myeloid leukemia in chronic phase (CML-CP) previously treated with ≥2 tyrosine kinase inhibitors (TKIs). Blood, 136. https://doi.org/10.1182/BLOOD-2020-143816

Efficacy and safety results from ASCEMBL, a multicenter, open-label, phase 3 study of asciminib, a first-in-class STAMP inhibitor, vs bosutinib (BOS) in patients (Pts) with chronic myeloid leukemia in chronic phase (CML-CP) previously treated with ≥2 tyrosine kinase inhibitors (TKIs). / Hochhaus, Andreas; Boquimpani, Carla; Rea, Delphine et al.
In: Blood, Vol. 136, 19.11.2020.

Research output: Contribution to journal › Article › peer-review

Hochhaus, A, Boquimpani, C, Rea, D, Minami, Y, Lomaia, E, Voloshin, S, Turkina, AG, Kim, DW, Apperley, J, Cortes, JE, Abdo, A, Fogliatto, LM, Kim, DDH, le Coutre, PD, Saussele, S, Annunziata, M, Hughes, TP, Chaudhri, NA, Chee, LCY, Gutiérrez, VG, Sasaki, K, Aimone, P, Allepuz, A, Quenet, S, Bédoucha, V & Mauro, MJ 2020, 'Efficacy and safety results from ASCEMBL, a multicenter, open-label, phase 3 study of asciminib, a first-in-class STAMP inhibitor, vs bosutinib (BOS) in patients (Pts) with chronic myeloid leukemia in chronic phase (CML-CP) previously treated with ≥2 tyrosine kinase inhibitors (TKIs)', Blood, vol. 136. https://doi.org/10.1182/BLOOD-2020-143816

Hochhaus A, Boquimpani C, Rea D, Minami Y, Lomaia E, Voloshin S et al. Efficacy and safety results from ASCEMBL, a multicenter, open-label, phase 3 study of asciminib, a first-in-class STAMP inhibitor, vs bosutinib (BOS) in patients (Pts) with chronic myeloid leukemia in chronic phase (CML-CP) previously treated with ≥2 tyrosine kinase inhibitors (TKIs). Blood. 2020 Nov 19;136. doi: 10.1182/BLOOD-2020-143816

Hochhaus, Andreas ; Boquimpani, Carla ; Rea, Delphine et al. / Efficacy and safety results from ASCEMBL, a multicenter, open-label, phase 3 study of asciminib, a first-in-class STAMP inhibitor, vs bosutinib (BOS) in patients (Pts) with chronic myeloid leukemia in chronic phase (CML-CP) previously treated with ≥2 tyrosine kinase inhibitors (TKIs). In: Blood. 2020 ; Vol. 136.

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AU - Hochhaus, Andreas

AU - Boquimpani, Carla

AU - Rea, Delphine

AU - Minami, Yosuke

AU - Lomaia, Elza

AU - Voloshin, Sergey

AU - Turkina, Anna G.

AU - Kim, Dong Wook

AU - Apperley, Jane

AU - Cortes, Jorge E.

AU - Abdo, Andre

AU - Fogliatto, Laura Maria

AU - Kim, Dennis Dong Hwan

AU - le Coutre, Philipp D.

AU - Saussele, Susanne

AU - Annunziata, Mario

AU - Hughes, Timothy P.

AU - Chaudhri, Naeem A.

AU - Chee, Lynette C.Y.

AU - Gutiérrez, Valentín García

AU - Sasaki, Koji

AU - Aimone, Paola

AU - Allepuz, Alex

AU - Quenet, Sarah

AU - Bédoucha, Véronique

AU - Mauro, Michael J.

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Efficacy and safety results from ASCEMBL, a multicenter, open-label, phase 3 study of asciminib, a first-in-class STAMP inhibitor, vs bosutinib (BOS) in patients (Pts) with chronic myeloid leukemia in chronic phase (CML-CP) previously treated with ≥2 tyrosine kinase inhibitors (TKIs)

ASJC Scopus subject areas

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