Embryos generated using testicular spermatozoa have higher developmental potential than those obtained using epididymal spermatozoa in men with obstructive azoospermia

Dmitri Dozortsev; Rosa Neme; Michael P. Diamond; Soraya Abdelmassih; Vicente Abdelmassih; Flavio Oliveira; Roger Abdelmassih

doi:10.1016/j.fertnstert.2006.01.036

Embryos generated using testicular spermatozoa have higher developmental potential than those obtained using epididymal spermatozoa in men with obstructive azoospermia

Dmitri Dozortsev, Rosa Neme, Michael P. Diamond, Soraya Abdelmassih, Vicente Abdelmassih, Flavio Oliveira, Roger Abdelmassih

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

Objective: To determine whether the injection of testicular spermatozoa results in more viable embryos (higher implantation rate) than injection of epididymal spermatozoa in cases of obstructive azoospermia. Design: Retrospective analysis of 265 cases of testicular sperm aspiration (TESA) and percutaneous sperm aspiration (PESA), including 185 cases of obstructive azoospermia. Setting: Private Infertility clinic. Patient(s): None, charts review. Intervention(s): None, charts review. Main Outcome Measure(s): Clinical pregnancy rate (PR), implantation rate. Result(s): Although fertilization rates were higher in the PESA group, implantation rates were significantly better in the TESA group. There was also a trend to higher ongoing PR and lower miscarriage rates in TESA cases. Conclusion(s): In cases of obstructive azoospermia, embryos generated using testicular spermatozoa have higher developmental potential than those obtained using epididymal spermatozoa.

Original language	English (US)
Pages (from-to)	606-611
Number of pages	6
Journal	Fertility and sterility
Volume	86
Issue number	3
DOIs	https://doi.org/10.1016/j.fertnstert.2006.01.036
State	Published - Sep 2006
Externally published	Yes

Keywords

Obstructive azoospermia
PESA
TESA
fertilization rate
miscarriage
pregnancy rate

ASJC Scopus subject areas

Reproductive Medicine
Obstetrics and Gynecology

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10.1016/j.fertnstert.2006.01.036

Cite this

Dozortsev, D., Neme, R., Diamond, M. P., Abdelmassih, S., Abdelmassih, V., Oliveira, F., & Abdelmassih, R. (2006). Embryos generated using testicular spermatozoa have higher developmental potential than those obtained using epididymal spermatozoa in men with obstructive azoospermia. Fertility and sterility, 86(3), 606-611. https://doi.org/10.1016/j.fertnstert.2006.01.036

Dozortsev, D, Neme, R, Diamond, MP, Abdelmassih, S, Abdelmassih, V, Oliveira, F & Abdelmassih, R 2006, 'Embryos generated using testicular spermatozoa have higher developmental potential than those obtained using epididymal spermatozoa in men with obstructive azoospermia', Fertility and sterility, vol. 86, no. 3, pp. 606-611. https://doi.org/10.1016/j.fertnstert.2006.01.036

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abstract = "Objective: To determine whether the injection of testicular spermatozoa results in more viable embryos (higher implantation rate) than injection of epididymal spermatozoa in cases of obstructive azoospermia. Design: Retrospective analysis of 265 cases of testicular sperm aspiration (TESA) and percutaneous sperm aspiration (PESA), including 185 cases of obstructive azoospermia. Setting: Private Infertility clinic. Patient(s): None, charts review. Intervention(s): None, charts review. Main Outcome Measure(s): Clinical pregnancy rate (PR), implantation rate. Result(s): Although fertilization rates were higher in the PESA group, implantation rates were significantly better in the TESA group. There was also a trend to higher ongoing PR and lower miscarriage rates in TESA cases. Conclusion(s): In cases of obstructive azoospermia, embryos generated using testicular spermatozoa have higher developmental potential than those obtained using epididymal spermatozoa.",

keywords = "Obstructive azoospermia, PESA, TESA, fertilization rate, miscarriage, pregnancy rate",

author = "Dmitri Dozortsev and Rosa Neme and Diamond, {Michael P.} and Soraya Abdelmassih and Vicente Abdelmassih and Flavio Oliveira and Roger Abdelmassih",

year = "2006",

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doi = "10.1016/j.fertnstert.2006.01.036",

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AU - Dozortsev, Dmitri

AU - Neme, Rosa

AU - Diamond, Michael P.

AU - Abdelmassih, Soraya

AU - Abdelmassih, Vicente

AU - Oliveira, Flavio

AU - Abdelmassih, Roger

PY - 2006/9

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N2 - Objective: To determine whether the injection of testicular spermatozoa results in more viable embryos (higher implantation rate) than injection of epididymal spermatozoa in cases of obstructive azoospermia. Design: Retrospective analysis of 265 cases of testicular sperm aspiration (TESA) and percutaneous sperm aspiration (PESA), including 185 cases of obstructive azoospermia. Setting: Private Infertility clinic. Patient(s): None, charts review. Intervention(s): None, charts review. Main Outcome Measure(s): Clinical pregnancy rate (PR), implantation rate. Result(s): Although fertilization rates were higher in the PESA group, implantation rates were significantly better in the TESA group. There was also a trend to higher ongoing PR and lower miscarriage rates in TESA cases. Conclusion(s): In cases of obstructive azoospermia, embryos generated using testicular spermatozoa have higher developmental potential than those obtained using epididymal spermatozoa.

AB - Objective: To determine whether the injection of testicular spermatozoa results in more viable embryos (higher implantation rate) than injection of epididymal spermatozoa in cases of obstructive azoospermia. Design: Retrospective analysis of 265 cases of testicular sperm aspiration (TESA) and percutaneous sperm aspiration (PESA), including 185 cases of obstructive azoospermia. Setting: Private Infertility clinic. Patient(s): None, charts review. Intervention(s): None, charts review. Main Outcome Measure(s): Clinical pregnancy rate (PR), implantation rate. Result(s): Although fertilization rates were higher in the PESA group, implantation rates were significantly better in the TESA group. There was also a trend to higher ongoing PR and lower miscarriage rates in TESA cases. Conclusion(s): In cases of obstructive azoospermia, embryos generated using testicular spermatozoa have higher developmental potential than those obtained using epididymal spermatozoa.

KW - Obstructive azoospermia

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KW - TESA

KW - fertilization rate

KW - miscarriage

KW - pregnancy rate

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Embryos generated using testicular spermatozoa have higher developmental potential than those obtained using epididymal spermatozoa in men with obstructive azoospermia

Abstract

Keywords

ASJC Scopus subject areas

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