Endotoxin adherence to and elution from two casting alloys

Kent I. Knovrnschild, Carol A. Lefebvre, George S. Schuster, Use M. Payant, Francois M. Gagnon

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


The purpose of this study was to compare tbe relative affinity of bacterial lipopolysaccbaride for two casting alloys with varied surface finisbes by measuring lipopolysaccharide adberence and elution. Air borne particle abraded and polisbed Rexillium III and Harmony Hard alloy discs were exposed to 600,000 endotoxin unlts/mL E. coli lipopolysaccbaride in water for 24 bours, whereas control discs were placed in 37°C, lipopolysaccharidefree water. Lipopolysaccbarlde-exposed and control discs were tben transferred every 24 hours to fresh, lipopolysaccharide-free water for up to 96 hours, and previously incubated eluates were tested for the presence of lipopolysaccbaride. Initial lipopolysaccbaride adherence to abraded Rexillium III discs was significantly greater than lipopolysaccharide adherence to the other groups (P < .05). Polished and abraded Rexillium III also exhibited significantly greater lipopolysaccharide elution (P = .0001. However, after 96 hours, more than 99% of the initially adbering lipopolysaccharide remained on both Rexillium 111 and Harmony Hard discs, regardless of surface treatment.

Original languageEnglish (US)
Pages (from-to)22-29
Number of pages8
JournalInternational Journal of Prosthodontics
Issue number1
StatePublished - 1994

ASJC Scopus subject areas

  • Oral Surgery


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