Abstract
A monoclonal diffuse histiocytic lymphoma developed during the course of a serologically documented primary Epstein-Barr virus infection in a 22-year-old cardiac transplant recipient taking cyclosporine and prednisone. Throat washings revealed the virus at tumor presentation, and the tumor was shown to contain EpsteinBarr nuclear antigen-positive cells and the viral genome. Prolonged inversion of the T cell helper/suppressor ratio was demonstrated. A brief course of acyclovir appeared to halt viral shedding in the throat but had no apparent effect on the tumor.
Original language | English (US) |
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Pages (from-to) | 179-184 |
Number of pages | 6 |
Journal | The American Journal of Medicine |
Volume | 77 |
Issue number | 1 |
DOIs | |
State | Published - Jul 1984 |
Externally published | Yes |
ASJC Scopus subject areas
- General Medicine