Epstein-barr virus-induced lymphoma in a cardiac transplant recipient

J. Stephen Dummer; Linda M. Bound; Gurmukh Singh; R. Wayne Atchison; Silloo B. Kapadia; Monto HO

doi:10.1016/0002-9343(84)90458-3

Epstein-barr virus-induced lymphoma in a cardiac transplant recipient

J. Stephen Dummer
, Linda M. Bound
, Gurmukh Singh
, R. Wayne Atchison
, Silloo B. Kapadia
, Monto HO

Research output: Contribution to journal › Article › peer-review

35 Scopus citations

Abstract

A monoclonal diffuse histiocytic lymphoma developed during the course of a serologically documented primary Epstein-Barr virus infection in a 22-year-old cardiac transplant recipient taking cyclosporine and prednisone. Throat washings revealed the virus at tumor presentation, and the tumor was shown to contain EpsteinBarr nuclear antigen-positive cells and the viral genome. Prolonged inversion of the T cell helper/suppressor ratio was demonstrated. A brief course of acyclovir appeared to halt viral shedding in the throat but had no apparent effect on the tumor.

Original language	English (US)
Pages (from-to)	179-184
Number of pages	6
Journal	The American Journal of Medicine
Volume	77
Issue number	1
DOIs	https://doi.org/10.1016/0002-9343(84)90458-3
State	Published - Jul 1984
Externally published	Yes

ASJC Scopus subject areas

General Medicine

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10.1016/0002-9343(84)90458-3

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title = "Epstein-barr virus-induced lymphoma in a cardiac transplant recipient",

abstract = "A monoclonal diffuse histiocytic lymphoma developed during the course of a serologically documented primary Epstein-Barr virus infection in a 22-year-old cardiac transplant recipient taking cyclosporine and prednisone. Throat washings revealed the virus at tumor presentation, and the tumor was shown to contain EpsteinBarr nuclear antigen-positive cells and the viral genome. Prolonged inversion of the T cell helper/suppressor ratio was demonstrated. A brief course of acyclovir appeared to halt viral shedding in the throat but had no apparent effect on the tumor.",

author = "Dummer, \{J. Stephen\} and Bound, \{Linda M.\} and Gurmukh Singh and Atchison, \{R. Wayne\} and Kapadia, \{Silloo B.\} and Monto HO",

year = "1984",

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AU - Dummer, J. Stephen

AU - Bound, Linda M.

AU - Singh, Gurmukh

AU - Atchison, R. Wayne

AU - Kapadia, Silloo B.

AU - HO, Monto

PY - 1984/7

Y1 - 1984/7

N2 - A monoclonal diffuse histiocytic lymphoma developed during the course of a serologically documented primary Epstein-Barr virus infection in a 22-year-old cardiac transplant recipient taking cyclosporine and prednisone. Throat washings revealed the virus at tumor presentation, and the tumor was shown to contain EpsteinBarr nuclear antigen-positive cells and the viral genome. Prolonged inversion of the T cell helper/suppressor ratio was demonstrated. A brief course of acyclovir appeared to halt viral shedding in the throat but had no apparent effect on the tumor.

AB - A monoclonal diffuse histiocytic lymphoma developed during the course of a serologically documented primary Epstein-Barr virus infection in a 22-year-old cardiac transplant recipient taking cyclosporine and prednisone. Throat washings revealed the virus at tumor presentation, and the tumor was shown to contain EpsteinBarr nuclear antigen-positive cells and the viral genome. Prolonged inversion of the T cell helper/suppressor ratio was demonstrated. A brief course of acyclovir appeared to halt viral shedding in the throat but had no apparent effect on the tumor.

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JF - The American Journal of Medicine

IS - 1

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Epstein-barr virus-induced lymphoma in a cardiac transplant recipient

Abstract

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