TY - JOUR
T1 - Evaluation of gastrointestinal transit in clinical practice
T2 - Position paper of the American and European Neurogastroenterology and Motility Societies
AU - Rao, S. S.C.
AU - Camilleri, M.
AU - Hasler, W. L.
AU - Maurer, A. H.
AU - Parkman, H. P.
AU - Saad, R.
AU - Scott, M. S.
AU - Simren, M.
AU - Soffer, E.
AU - Szarka, L.
PY - 2011/1
Y1 - 2011/1
N2 - Background: Disorders of gastrointestinal (GI) transit and motility are common, and cause either delayed or accelerated transit through the stomach, small intestine or colon, and affect one or more regions. Assessment of regional and/or whole gut transit times can provide direct measurements and diagnostic information to explain the cause of symptoms, and plan therapy.Purpose: Recently, several newer diagnostic tools have become available. The American and European Neurogastroenterology and Motility Societies undertook this review to provide guidelines on the indications and optimal methods for the use of transit measurements in clinical practice. This was based on evidence of validation including performance characteristics, clinical significance, and strengths of various techniques. The tests include measurements of: gastric emptying with scintigraphy, wireless motility capsule, and 13C breath tests; small bowel transit with breath tests, scintigraphy, and wireless motility capsule; and colonic transit with radioopaque markers, wireless motility capsule, and scintigraphy. Based on the evidence, consensus recommendations are provided for each technique and for the evaluations of regional and whole gut transit. In summary, tests of gastrointestinal transit are available and useful in the evaluation of patients with symptoms suggestive of gastrointestinal dysmotility, since they can provide objective diagnosis and a rational approach to patient management.
AB - Background: Disorders of gastrointestinal (GI) transit and motility are common, and cause either delayed or accelerated transit through the stomach, small intestine or colon, and affect one or more regions. Assessment of regional and/or whole gut transit times can provide direct measurements and diagnostic information to explain the cause of symptoms, and plan therapy.Purpose: Recently, several newer diagnostic tools have become available. The American and European Neurogastroenterology and Motility Societies undertook this review to provide guidelines on the indications and optimal methods for the use of transit measurements in clinical practice. This was based on evidence of validation including performance characteristics, clinical significance, and strengths of various techniques. The tests include measurements of: gastric emptying with scintigraphy, wireless motility capsule, and 13C breath tests; small bowel transit with breath tests, scintigraphy, and wireless motility capsule; and colonic transit with radioopaque markers, wireless motility capsule, and scintigraphy. Based on the evidence, consensus recommendations are provided for each technique and for the evaluations of regional and whole gut transit. In summary, tests of gastrointestinal transit are available and useful in the evaluation of patients with symptoms suggestive of gastrointestinal dysmotility, since they can provide objective diagnosis and a rational approach to patient management.
KW - Breath tests
KW - Dysmotility
KW - Gastrointestinal transit
KW - Radioopaque markers
KW - Scintigraphy
KW - Wireless motility capsule
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U2 - 10.1111/j.1365-2982.2010.01612.x
DO - 10.1111/j.1365-2982.2010.01612.x
M3 - Review article
C2 - 21138500
AN - SCOPUS:78650154193
SN - 1350-1925
VL - 23
SP - 8
EP - 23
JO - Neurogastroenterology and Motility
JF - Neurogastroenterology and Motility
IS - 1
ER -