TY - JOUR
T1 - Expert consensus document
T2 - Advances in the evaluation of anorectal function
AU - on behalf of the International Anorectal Physiology Working Group and the International Working Group for Disorders of Gastrointestinal Motility and Function
AU - Carrington, Emma V.
AU - Scott, S. Mark
AU - Bharucha, Adil
AU - Mion, François
AU - Remes-Troche, Jose M.
AU - Malcolm, Allison
AU - Heinrich, Henriette
AU - Fox, Mark
AU - Rao, Satish S.
N1 - Funding Information:
E.V.C. has received honoraria for teaching from Medical Measurement Systems/Laborie. S.M.S. has received honoraria for teaching from Medical Measurement Systems/ Laborie. A.B. has licensed intellectual property in a portable anorectal manometry device to Medspira. F.M. has served as consultant for Medtronic and Medical Measurement Systems/ Laborie. J.M.R.-T. has received research funding from Newton Foundation–CONACYT, Sanfer and Asofarma Laboratories and speaker fees from Covidien/Medtronics, Takeda, Allergan, AstraZeneca, Sanofi and Sanfer. M.F. has received research funding from Covidien/Medtronic and speaker fees from Covidien/Medtronic, Sandhill, Medical Measurement Systems/ Laborie, Reckitt Benckiser and Mui Scientific. S.S.R. has served on advisory boards for Forest Laboratories, Synergy Pharmaceuticals, Vibrant and InTone and has received research grants from Forest Laboratories, Synergy, InTone and Medtronic. H.H. and A.M. declare no competing interests.
Funding Information:
The International Working Group for Disorders of Gastrointestinal Motility and Function initiated the consensus meetings and provided material support for the consensus process. Five separate groups reviewed the current state-of-the-art in clinical measurement of gastrointestinal motility and function: oropharynx, oesophagus, reflux disease, stomach/intestine and anorectum. This process was endorsed by the European Society of Neurogastroenterology and Motility (ESNM), and the European Society of Colo-Proctology (ESCP) with representation and support from members of the American Neurogastroenterology and Motility Society (ANMS), the South American and Latin Society (SLNG), the Asian Neurogastroenterology and Motility Association (ANMA) and the Australasian Neurogastroenterology and Motility Association (ANGMA). Financial support was provided by the United European Gastroenterology (UEG) Education Committee, registration fees for meetings and sponsorship from major manufacturers of physiological measurement equipment. AB is supported by USPHS NIH Grant DKDK78924.
Publisher Copyright:
© 2018 Macmillan Publishers Limited, part of Springer Nature.
PY - 2018/5/1
Y1 - 2018/5/1
N2 - Faecal incontinence and evacuation disorders are common, impair quality of life and incur substantial economic costs worldwide. As symptoms alone are poor predictors of underlying pathophysiology and aetiology, diagnostic tests of anorectal function could facilitate patient management in those cases that are refractory to conservative therapies. In the past decade, several major technological advances have improved our understanding of anorectal structure, coordination and sensorimotor function. This Consensus Statement provides the reader with an appraisal of the current indications, study performance characteristics, clinical utility, strengths and limitations of the most widely available tests of anorectal structure (ultrasonography and MRI) and function (anorectal manometry, neurophysiological investigations, rectal distension techniques and tests of evacuation, including defecography). Additionally, this article provides our consensus on the clinical relevance of these tests.
AB - Faecal incontinence and evacuation disorders are common, impair quality of life and incur substantial economic costs worldwide. As symptoms alone are poor predictors of underlying pathophysiology and aetiology, diagnostic tests of anorectal function could facilitate patient management in those cases that are refractory to conservative therapies. In the past decade, several major technological advances have improved our understanding of anorectal structure, coordination and sensorimotor function. This Consensus Statement provides the reader with an appraisal of the current indications, study performance characteristics, clinical utility, strengths and limitations of the most widely available tests of anorectal structure (ultrasonography and MRI) and function (anorectal manometry, neurophysiological investigations, rectal distension techniques and tests of evacuation, including defecography). Additionally, this article provides our consensus on the clinical relevance of these tests.
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U2 - 10.1038/nrgastro.2018.27
DO - 10.1038/nrgastro.2018.27
M3 - Review article
C2 - 29636555
AN - SCOPUS:85045905940
SN - 1759-5045
VL - 15
SP - 309
EP - 325
JO - Nature Reviews Gastroenterology and Hepatology
JF - Nature Reviews Gastroenterology and Hepatology
IS - 5
ER -