Fifty years of impact on treating bone disease: a commentary on Gasser et al.

Elena L. Dent; Michael J. Ryan

doi:10.1042/CS20220040

Fifty years of impact on treating bone disease: a commentary on Gasser et al.

Elena L. Dent, Michael J. Ryan

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Abstract

The precise control of whole-body calcium is essential for the maintenance of normal physiological function. Disruptions in calcium homeostasis can lead to pathology including osteoporosis, kidney stone formation, and cardiac arrythmias. During the 1960s and early 1970s, a full understanding of calcium metabolism was still emerging. This commentary spotlights a seminal Clinical Science paper published in 1972 that significantly advanced the field and contributed to the eventual approval of bisphosphonate drugs commonly used to treat postmenopausal osteoporosis, cancer metastases, and other calcium disorders.

Original language	English (US)
Pages (from-to)	1657-1659
Number of pages	3
Journal	Clinical Science
Volume	136
Issue number	22
DOIs	https://doi.org/10.1042/CS20220040
State	Published - Nov 2022
Externally published	Yes

ASJC Scopus subject areas

General Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1042/CS20220040

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abstract = "The precise control of whole-body calcium is essential for the maintenance of normal physiological function. Disruptions in calcium homeostasis can lead to pathology including osteoporosis, kidney stone formation, and cardiac arrythmias. During the 1960s and early 1970s, a full understanding of calcium metabolism was still emerging. This commentary spotlights a seminal Clinical Science paper published in 1972 that significantly advanced the field and contributed to the eventual approval of bisphosphonate drugs commonly used to treat postmenopausal osteoporosis, cancer metastases, and other calcium disorders.",

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Fifty years of impact on treating bone disease: a commentary on Gasser et al.

Abstract

ASJC Scopus subject areas

UN SDGs

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