First-trimester Doppler investigation of the uterine circulation

Laura Detti, Samuel C. Johnson, Michael P. Diamond, Elizabeth E. Puscheck

Research output: Contribution to journalReview articlepeer-review

12 Scopus citations


There is now strong evidence that fetal events can significantly impact postnatal health and disease development. Doppler velocimetry can identify some early pathologic changes in pregnancy. Many investigators have tried to delineate the normal and pathologic models of the uterine circulation in the first trimester, but much has yet to be defined. A discrete amount of confusion derives from the incomplete knowledge of the initial placental development, and particularly the development of the intervillous circulation. This article comprehensively reviews the literature on first-trimester Doppler in both normal and complicated pregnancies, and briefly discusses potential future areas of application.

Original languageEnglish (US)
Pages (from-to)1210-1218
Number of pages9
JournalAmerican journal of obstetrics and gynecology
Issue number5
StatePublished - Nov 1 2006
Externally publishedYes


  • Blood flow
  • Doppler ultrasonography
  • First trimester
  • Placenta
  • Pregnancy
  • Review
  • Uterine circulation

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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