Future research directions in asthma: An NHLBI working group report

Bruce D. Levy; Patricia J. Noel; Michelle M. Freemer; Michelle M. Cloutier; Steve N. Georas; Nizar N. Jarjour; Carole Ober; Prescott G. Woodruff; Kathleen C. Barnes; Bruce G. Bender; Carlos A. Camargo; Geoff L. Chupp; Loren C. Denlinger; John V. Fahy; Anne M. Fitzpatrick; Anne Fuhlbrigge; Ben M. Gaston; Tina V. Hartert; Jay K. Kolls; Susan V. Lynch; Wendy C. Moore; Wayne J. Morgan; Kari C. Nadeau; Dennis Randall Ownby; Julian Solway; Stanley J. Szefler; Sally E. Wenzel; Rosalind J. Wright; Robert A. Smith; Serpil C. Erzurum

doi:10.1164/rccm.201505-0963WS

Future research directions in asthma: An NHLBI working group report

Bruce D. Levy, Patricia J. Noel, Michelle M. Freemer, Michelle M. Cloutier, Steve N. Georas, Nizar N. Jarjour, Carole Ober, Prescott G. Woodruff, Kathleen C. Barnes, Bruce G. Bender, Carlos A. Camargo, Geoff L. Chupp, Loren C. Denlinger, John V. Fahy, Anne M. Fitzpatrick, Anne Fuhlbrigge, Ben M. Gaston, Tina V. Hartert, Jay K. Kolls, Susan V. LynchWendy C. Moore, Wayne J. Morgan, Kari C. Nadeau, Dennis Randall Ownby, Julian Solway, Stanley J. Szefler, Sally E. Wenzel, Rosalind J. Wright, Robert A. Smith, Serpil C. Erzurum

Allergy-Immunology and Rheumatology

Research output: Contribution to journal › Article › peer-review

63 Scopus citations

Abstract

Asthma is a common chronic disease without cure. Our understanding of asthma onset, pathobiology, classification, and management has evolved substantially over the past decade; however, significant asthma-related morbidity and excess healthcare use and costs persist. To address this important clinical condition, the NHLBI convened a group of extramural investigators for an Asthma Research Strategic Planning workshop on September 18-19, 2014, to accelerate discoveries and their translation to patients. The workshop focused on (1) in utero and early-life origins of asthma, (2) the use of phenotypes and endotypes to classify disease, (3) defining disease modification, (4) disease management, and (5) implementation research. This report summarizes the workshop and produces recommendations to guide future research in asthma.

Original language	English (US)
Pages (from-to)	1366-1372
Number of pages	7
Journal	American journal of respiratory and critical care medicine
Volume	192
Issue number	11
DOIs	https://doi.org/10.1164/rccm.201505-0963WS
State	Published - Dec 1 2015

Keywords

Asthma
Disease modification
Implementation
Phenotype
Prevention

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine
Critical Care and Intensive Care Medicine

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Levy, B. D., Noel, P. J., Freemer, M. M., Cloutier, M. M., Georas, S. N., Jarjour, N. N., Ober, C., Woodruff, P. G., Barnes, K. C., Bender, B. G., Camargo, C. A., Chupp, G. L., Denlinger, L. C., Fahy, J. V., Fitzpatrick, A. M., Fuhlbrigge, A., Gaston, B. M., Hartert, T. V., Kolls, J. K., ... Erzurum, S. C. (2015). Future research directions in asthma: An NHLBI working group report. American journal of respiratory and critical care medicine, 192(11), 1366-1372. https://doi.org/10.1164/rccm.201505-0963WS

Levy, BD, Noel, PJ, Freemer, MM, Cloutier, MM, Georas, SN, Jarjour, NN, Ober, C, Woodruff, PG, Barnes, KC, Bender, BG, Camargo, CA, Chupp, GL, Denlinger, LC, Fahy, JV, Fitzpatrick, AM, Fuhlbrigge, A, Gaston, BM, Hartert, TV, Kolls, JK, Lynch, SV, Moore, WC, Morgan, WJ, Nadeau, KC, Ownby, DR, Solway, J, Szefler, SJ, Wenzel, SE, Wright, RJ, Smith, RA & Erzurum, SC 2015, 'Future research directions in asthma: An NHLBI working group report', American journal of respiratory and critical care medicine, vol. 192, no. 11, pp. 1366-1372. https://doi.org/10.1164/rccm.201505-0963WS

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Future research directions in asthma: An NHLBI working group report

Abstract

Keywords

ASJC Scopus subject areas

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