Abstract
Clustering of acetylcholine receptors (AChR) in muscle fibers prior to innervation by motor neurons is thought to be involved in neuromuscular junction formation. Jing et al. now report in Neuron that this prepatterning of AChRs, via a novel MuSK-dependent Wnt pathway, may guide motor axons to the central region of muscle fibers for synapse formation in zebrafish.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 325-327 |
| Number of pages | 3 |
| Journal | Developmental Cell |
| Volume | 16 |
| Issue number | 3 |
| DOIs | |
| State | Published - Mar 17 2009 |
ASJC Scopus subject areas
- Molecular Biology
- General Biochemistry, Genetics and Molecular Biology
- Developmental Biology
- Cell Biology