GRowing an epidermal tumor

Wendy B. Bollag; Carlos M. Isales

doi:10.1038/jid.2013.350

GRowing an epidermal tumor

Wendy B. Bollag, Carlos M. Isales

Research output: Contribution to journal › Comment/debate › peer-review

4 Scopus citations

Abstract

The glucocorticoid receptor (GR), a member of the nuclear hormone family of transcription factors, has key physiological roles in many organs, including the skin. In this issue, Latorre et al. demonstrate that mice lacking GR in the epidermis exhibit increased vulnerability to chemical carcinogenesis. Evidence supporting an involvement of GR signaling in physiological and pathophysiological processes in skin is discussed.

Original language	English (US)
Pages (from-to)	2659-2662
Number of pages	4
Journal	Journal of Investigative Dermatology
Volume	133
Issue number	12
DOIs	https://doi.org/10.1038/jid.2013.350
State	Published - Dec 2013

ASJC Scopus subject areas

Biochemistry
Molecular Biology
Dermatology
Cell Biology

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10.1038/jid.2013.350

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title = "GRowing an epidermal tumor",

abstract = "The glucocorticoid receptor (GR), a member of the nuclear hormone family of transcription factors, has key physiological roles in many organs, including the skin. In this issue, Latorre et al. demonstrate that mice lacking GR in the epidermis exhibit increased vulnerability to chemical carcinogenesis. Evidence supporting an involvement of GR signaling in physiological and pathophysiological processes in skin is discussed.",

author = "Bollag, {Wendy B.} and Isales, {Carlos M.}",

note = "Funding Information: This work was supported in part by a VA Research Career Scientist Award (WBB), a VA Merit Award (WBB), and National Institutes of Health award #P01AG036675 (WBB and CMI). The contents of this article do not represent the views of the Department of Veterans Affairs or the United States Government.",

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AU - Isales, Carlos M.

N1 - Funding Information: This work was supported in part by a VA Research Career Scientist Award (WBB), a VA Merit Award (WBB), and National Institutes of Health award #P01AG036675 (WBB and CMI). The contents of this article do not represent the views of the Department of Veterans Affairs or the United States Government.

PY - 2013/12

Y1 - 2013/12

N2 - The glucocorticoid receptor (GR), a member of the nuclear hormone family of transcription factors, has key physiological roles in many organs, including the skin. In this issue, Latorre et al. demonstrate that mice lacking GR in the epidermis exhibit increased vulnerability to chemical carcinogenesis. Evidence supporting an involvement of GR signaling in physiological and pathophysiological processes in skin is discussed.

AB - The glucocorticoid receptor (GR), a member of the nuclear hormone family of transcription factors, has key physiological roles in many organs, including the skin. In this issue, Latorre et al. demonstrate that mice lacking GR in the epidermis exhibit increased vulnerability to chemical carcinogenesis. Evidence supporting an involvement of GR signaling in physiological and pathophysiological processes in skin is discussed.

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JO - Journal of Investigative Dermatology

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GRowing an epidermal tumor

Abstract

ASJC Scopus subject areas

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