Hb las palms or α2β249(cd8)ser→phe, a mildly unstable hemiglobin variant

J. J. Malcorra-Azpiazu, H. I. Balda-Aguirre, J. C. Diaz-Chico, H. Hu, J. B. Wilson, B. B. Webber, F. Kutlar, A. Kutlar, T. H.J. Huisman

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


A new hemoglobin variant with a Ser→Phe substitution at position β 49(CD8) was discovered in two members of a family living in the Canary Islands, Spain. Detection was by polyacrylamide gel electrophoresis and by reversed phase high performance liquid chromatography. The variant, which constituted 43% and 45% respectively, in the two heterozygotes, was slightly unstable. Its presence did not affect hematological values though there was a mild reticulocytes.

Original languageEnglish (US)
Pages (from-to)163-170
Number of pages8
Issue number2
StatePublished - 1988

ASJC Scopus subject areas

  • Hematology
  • Genetics(clinical)
  • Clinical Biochemistry
  • Biochemistry, medical


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