High intensity focused ultrasound: The fundamentals, clinical applications and research trends

I. A.Shehata Elhelf; H. Albahar; U. Shah; A. Oto; E. Cressman; M. Almekkawy

doi:10.1016/j.diii.2018.03.001

High intensity focused ultrasound: The fundamentals, clinical applications and research trends

I. A.Shehata Elhelf, H. Albahar, U. Shah, A. Oto, E. Cressman, M. Almekkawy

Research output: Contribution to journal › Short survey › peer-review

152 Scopus citations

Abstract

Diagnostic ultrasound has been clinically used for decades. More recently, high intensity focused ultrasound (HIFU) has been developed for therapeutic use as a non-invasive technique for tissue ablation. HIFU is also being investigated for advanced applications at the cellular level. Under guidance by magnetic resonance or ultrasound imaging, HIFU can achieve precise biological effects in tissue with a high safety profile. In this article, we discuss the basic principles, advantages and limitations of HIFU. We will also address the food and drug administration (FDA) approved clinical applications in the United States and highlight active HIFU research with promising clinical outcomes.

Original language	English (US)
Pages (from-to)	349-359
Number of pages	11
Journal	Diagnostic and interventional imaging
Volume	99
Issue number	6
DOIs	https://doi.org/10.1016/j.diii.2018.03.001
State	Published - Jun 2018
Externally published	Yes

Keywords

High intensity focused ultrasound (HIFU)
Immunomodulation
Interventional oncology
Temperature sensitive liposomes
Thermal ablation

ASJC Scopus subject areas

Radiological and Ultrasound Technology
Radiology Nuclear Medicine and imaging

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10.1016/j.diii.2018.03.001

Cite this

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title = "High intensity focused ultrasound: The fundamentals, clinical applications and research trends",

abstract = "Diagnostic ultrasound has been clinically used for decades. More recently, high intensity focused ultrasound (HIFU) has been developed for therapeutic use as a non-invasive technique for tissue ablation. HIFU is also being investigated for advanced applications at the cellular level. Under guidance by magnetic resonance or ultrasound imaging, HIFU can achieve precise biological effects in tissue with a high safety profile. In this article, we discuss the basic principles, advantages and limitations of HIFU. We will also address the food and drug administration (FDA) approved clinical applications in the United States and highlight active HIFU research with promising clinical outcomes.",

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T2 - The fundamentals, clinical applications and research trends

AU - Elhelf, I. A.Shehata

AU - Albahar, H.

AU - Shah, U.

AU - Oto, A.

AU - Cressman, E.

AU - Almekkawy, M.

PY - 2018/6

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AB - Diagnostic ultrasound has been clinically used for decades. More recently, high intensity focused ultrasound (HIFU) has been developed for therapeutic use as a non-invasive technique for tissue ablation. HIFU is also being investigated for advanced applications at the cellular level. Under guidance by magnetic resonance or ultrasound imaging, HIFU can achieve precise biological effects in tissue with a high safety profile. In this article, we discuss the basic principles, advantages and limitations of HIFU. We will also address the food and drug administration (FDA) approved clinical applications in the United States and highlight active HIFU research with promising clinical outcomes.

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KW - Immunomodulation

KW - Interventional oncology

KW - Temperature sensitive liposomes

KW - Thermal ablation

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High intensity focused ultrasound: The fundamentals, clinical applications and research trends

Abstract

Keywords

ASJC Scopus subject areas

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