Histopathological lesions in the brain of a teleost Anabas testudineus exposed to monocrotophos

M. Santhakumar, M. Balaji, K. Ramudu

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Pathological effects of monocrotophos has been studied on the brain by exposing the fish to sublethal concentrations 1.9,4.75 and 9.5 pp.m (1/10, 1/4, 1/2 of 96-h LC50) for 21 days. The histopathological changes were found to be dose dependent. The pesticide produced rupture of cortex, atrophy of molecular and granular layer, necrosis of neurofibrillar region, vascular dilation, nuclear pyknosis, fibrosis, vacuolation, cerebral oedema and interzonal detachment. Such changes may affect the proper survival of the fish in its aquatic environment.

Original languageEnglish (US)
Pages (from-to)297-299
Number of pages3
JournalJournal of Environmental Biology
Issue number4
StatePublished - Oct 2000
Externally publishedYes


  • Anabas testudineus
  • Brain
  • Histology
  • Monocrotophos

ASJC Scopus subject areas

  • Environmental Engineering
  • Toxicology
  • Health, Toxicology and Mutagenesis


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