TY - JOUR
T1 - Idiopathic dilated cardiomyopathy
AU - Cooke, Catherine E.
AU - Greenberg, Michael D.
AU - Coughlin, Steven S.
AU - Mishark, Kenneth
AU - Odawara, Masato
AU - Yamashita, Kamejiro
AU - Legha, Sewa S.
AU - Dec, G. W.
AU - Fuster, Valentin
PY - 1995/5/18
Y1 - 1995/5/18
N2 - To the Editor: Dec and Fuster (Dec. 8 issue)1 categorized the use of beta-blockers in patients with idiopathic dilated cardiomyopathy as investigational. There is now sufficient evidence to support their use as adjunctive therapy. Numerous clinical trials have evaluated the use of beta-blockers in conjunction with angiotensin-converting—enzyme inhibitors, nitrates, diuretics, and digoxin in patients with idiopathic dilated cardiomyopathy and have found improvements in ejection fraction, cardiac index, and New York Heart Association class and a decreased number of hospital admissions and cardiac transplantations.2—4 However, there have been trials5,6 that did not show such improvements. This is probably because.
AB - To the Editor: Dec and Fuster (Dec. 8 issue)1 categorized the use of beta-blockers in patients with idiopathic dilated cardiomyopathy as investigational. There is now sufficient evidence to support their use as adjunctive therapy. Numerous clinical trials have evaluated the use of beta-blockers in conjunction with angiotensin-converting—enzyme inhibitors, nitrates, diuretics, and digoxin in patients with idiopathic dilated cardiomyopathy and have found improvements in ejection fraction, cardiac index, and New York Heart Association class and a decreased number of hospital admissions and cardiac transplantations.2—4 However, there have been trials5,6 that did not show such improvements. This is probably because.
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U2 - 10.1056/NEJM199505183322015
DO - 10.1056/NEJM199505183322015
M3 - Letter
C2 - 7772174
AN - SCOPUS:0029647395
SN - 0028-4793
VL - 332
SP - 1384
EP - 1386
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 20
ER -