Improving neuron-to-electrode Surface attachment via alkanethiol self-assembly: An alternating current impedance study

Gymama E. Slaughter; Erhard Bieberich; Gary E. Wnek; Kenneth J. Wynne; Anthony Guiseppi-Elie

doi:10.1021/la049192s

Improving neuron-to-electrode Surface attachment via alkanethiol self-assembly: An alternating current impedance study

Gymama E. Slaughter, Erhard Bieberich, Gary E. Wnek, Kenneth J. Wynne, Anthony Guiseppi-Elie

Graduate Studies

Research output: Contribution to journal › Article › peer-review

43 Scopus citations

Abstract

The phenomena of neuron-to-electrode surface attachment NESA) via self-assembly of alkanethiol was investigated. The phenomena of hysteresis indicated cysteamine (CA) self-assembly monolayers (SAM) displays greater amphiphilic character than 11-amino-1-undecanethiol (11-AUT)-SAM. The tapping mode atomic force microscopy (AFM) also confirmed 6% increase and 22% decrease in surface roughness when compared to clean, unmodified and sputter-deposited gold. The results show that covalent immobilization of adhesion-promoting proteins enhanced NESA by tightly anchoring cells to electrode.

Original language	English (US)
Pages (from-to)	7189-7200
Number of pages	12
Journal	Langmuir
Volume	20
Issue number	17
DOIs	https://doi.org/10.1021/la049192s
State	Published - Aug 17 2004

ASJC Scopus subject areas

General Materials Science
Condensed Matter Physics
Surfaces and Interfaces
Spectroscopy
Electrochemistry

Access to Document

10.1021/la049192s

Cite this

@article{389ef12008404b4c9d91c57722e69171,

title = "Improving neuron-to-electrode Surface attachment via alkanethiol self-assembly: An alternating current impedance study",

abstract = "The phenomena of neuron-to-electrode surface attachment NESA) via self-assembly of alkanethiol was investigated. The phenomena of hysteresis indicated cysteamine (CA) self-assembly monolayers (SAM) displays greater amphiphilic character than 11-amino-1-undecanethiol (11-AUT)-SAM. The tapping mode atomic force microscopy (AFM) also confirmed 6% increase and 22% decrease in surface roughness when compared to clean, unmodified and sputter-deposited gold. The results show that covalent immobilization of adhesion-promoting proteins enhanced NESA by tightly anchoring cells to electrode.",

author = "Slaughter, {Gymama E.} and Erhard Bieberich and Wnek, {Gary E.} and Wynne, {Kenneth J.} and Anthony Guiseppi-Elie",

year = "2004",

month = aug,

day = "17",

doi = "10.1021/la049192s",

language = "English (US)",

volume = "20",

pages = "7189--7200",

journal = "Langmuir",

issn = "0743-7463",

publisher = "American Chemical Society",

number = "17",

}

TY - JOUR

T1 - Improving neuron-to-electrode Surface attachment via alkanethiol self-assembly

T2 - An alternating current impedance study

AU - Slaughter, Gymama E.

AU - Bieberich, Erhard

AU - Wnek, Gary E.

AU - Wynne, Kenneth J.

AU - Guiseppi-Elie, Anthony

PY - 2004/8/17

Y1 - 2004/8/17

N2 - The phenomena of neuron-to-electrode surface attachment NESA) via self-assembly of alkanethiol was investigated. The phenomena of hysteresis indicated cysteamine (CA) self-assembly monolayers (SAM) displays greater amphiphilic character than 11-amino-1-undecanethiol (11-AUT)-SAM. The tapping mode atomic force microscopy (AFM) also confirmed 6% increase and 22% decrease in surface roughness when compared to clean, unmodified and sputter-deposited gold. The results show that covalent immobilization of adhesion-promoting proteins enhanced NESA by tightly anchoring cells to electrode.

AB - The phenomena of neuron-to-electrode surface attachment NESA) via self-assembly of alkanethiol was investigated. The phenomena of hysteresis indicated cysteamine (CA) self-assembly monolayers (SAM) displays greater amphiphilic character than 11-amino-1-undecanethiol (11-AUT)-SAM. The tapping mode atomic force microscopy (AFM) also confirmed 6% increase and 22% decrease in surface roughness when compared to clean, unmodified and sputter-deposited gold. The results show that covalent immobilization of adhesion-promoting proteins enhanced NESA by tightly anchoring cells to electrode.

UR - http://www.scopus.com/inward/record.url?scp=4344713124&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=4344713124&partnerID=8YFLogxK

U2 - 10.1021/la049192s

DO - 10.1021/la049192s

M3 - Article

C2 - 15301505

AN - SCOPUS:4344713124

SN - 0743-7463

VL - 20

SP - 7189

EP - 7200

JO - Langmuir

JF - Langmuir

IS - 17

ER -

Improving neuron-to-electrode Surface attachment via alkanethiol self-assembly: An alternating current impedance study

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this