In vivo and in vitro permeability of one-step self-etch adhesives

S. Chersoni, P. Suppa, S. Grandini, C. Goracci, F. Monticelli, C. Yiu, C. Huang, C. Prati, L. Breschi, M. Ferrari, D. H. Pashley, F. R. Tay

Research output: Contribution to journalArticlepeer-review

129 Scopus citations


Adhesive dentistry should effectively restore the peripheral seal of dentin after enamel removal. We hypothesize that non-rinsing, simplified, one-step self-etch adhesives are effective for minimizing dentin permeability after tooth preparation procedures. Crown preparations in vital human teeth were sealed with Adper Prompt, Xeno III, iBond, or One-Up Bond F. Epoxy resin replicas were produced from polyvinyl siloxane impressions for SEM examination. Dentin surfaces from extracted human teeth were bonded with these adhesives and connected to a fluid-transport model for permeability measurements and TEM examination. Dentinal fluid droplets were observed from adhesive surfaces in resin replicas of in vivo specimens. In vitro fluid conductance of dentin bonded with one-step self-etch adhesives was either similar to or greater than that of smear-layer-covered dentin. TEM revealed water trees within the adhesives that facilitate water movement across the polymerized, highly permeable adhesives. Both in vitro and in vivo results did not support the proposed hypothesis.

Original languageEnglish (US)
Pages (from-to)459-464
Number of pages6
JournalJournal of Dental Research
Issue number6
StatePublished - Jun 2004
Externally publishedYes


  • In vivo
  • One-step self-etch
  • Permeability
  • Resin replica
  • Water tree

ASJC Scopus subject areas

  • Dentistry(all)


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