In vivo confocal reflectance microscopy of congenital melanocytic nevi

Pantea Hashemi; Ashfaq A. Marghoob; Harold S. Rabinovitz; Alon Scope

doi:10.1007/978-3-642-21997-9_11

In vivo confocal reflectance microscopy of congenital melanocytic nevi

Pantea Hashemi, Ashfaq A. Marghoob, Harold S. Rabinovitz, Alon Scope

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2 Scopus citations

Abstract

The presence of congenital melanocytic nevi (CMN) is determined in utero. CMN are neural crest-derived malformations, composed mainly of a benign proliferation of melanocytes. The most common method for the classification of CMN is based upon nevus size. Small CMN are defined as smaller than 1.5 cm in diameter, medium-sized CMN are 1.5–19.9 cm, large CMN are over 20 cm in diameter, and very large (i.e., giant CMN) are over 50 cm in diameter. Rational for the size-based classification is that there is an increased risk of developing melanoma, a larger cosmetic impact and a greater surgical complexity with increasing size of CMN. In addition, large and giant CMN are often intermixed with various other neural crest-derived elements such as neural tissue and may be associated with extra-cutaneous malformations such as neurocutaneous melanocytosis, dandy-walker malformation, and vascular anomalies [1].

Original language	English (US)
Title of host publication	Reflectance Confocal Microscopy for Skin Diseases
Publisher	Springer Berlin Heidelberg
Pages	115-131
Number of pages	17
ISBN (Electronic)	9783642219979
ISBN (Print)	9783642219962
DOIs	https://doi.org/10.1007/978-3-642-21997-9_11
State	Published - Jan 1 2012
Externally published	Yes

ASJC Scopus subject areas

General Medicine

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title = "In vivo confocal reflectance microscopy of congenital melanocytic nevi",

abstract = "The presence of congenital melanocytic nevi (CMN) is determined in utero. CMN are neural crest-derived malformations, composed mainly of a benign proliferation of melanocytes. The most common method for the classification of CMN is based upon nevus size. Small CMN are defined as smaller than 1.5 cm in diameter, medium-sized CMN are 1.5–19.9 cm, large CMN are over 20 cm in diameter, and very large (i.e., giant CMN) are over 50 cm in diameter. Rational for the size-based classification is that there is an increased risk of developing melanoma, a larger cosmetic impact and a greater surgical complexity with increasing size of CMN. In addition, large and giant CMN are often intermixed with various other neural crest-derived elements such as neural tissue and may be associated with extra-cutaneous malformations such as neurocutaneous melanocytosis, dandy-walker malformation, and vascular anomalies [1].",

author = "Pantea Hashemi and Marghoob, {Ashfaq A.} and Rabinovitz, {Harold S.} and Alon Scope",

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T1 - In vivo confocal reflectance microscopy of congenital melanocytic nevi

AU - Hashemi, Pantea

AU - Marghoob, Ashfaq A.

AU - Rabinovitz, Harold S.

AU - Scope, Alon

PY - 2012/1/1

Y1 - 2012/1/1

N2 - The presence of congenital melanocytic nevi (CMN) is determined in utero. CMN are neural crest-derived malformations, composed mainly of a benign proliferation of melanocytes. The most common method for the classification of CMN is based upon nevus size. Small CMN are defined as smaller than 1.5 cm in diameter, medium-sized CMN are 1.5–19.9 cm, large CMN are over 20 cm in diameter, and very large (i.e., giant CMN) are over 50 cm in diameter. Rational for the size-based classification is that there is an increased risk of developing melanoma, a larger cosmetic impact and a greater surgical complexity with increasing size of CMN. In addition, large and giant CMN are often intermixed with various other neural crest-derived elements such as neural tissue and may be associated with extra-cutaneous malformations such as neurocutaneous melanocytosis, dandy-walker malformation, and vascular anomalies [1].

AB - The presence of congenital melanocytic nevi (CMN) is determined in utero. CMN are neural crest-derived malformations, composed mainly of a benign proliferation of melanocytes. The most common method for the classification of CMN is based upon nevus size. Small CMN are defined as smaller than 1.5 cm in diameter, medium-sized CMN are 1.5–19.9 cm, large CMN are over 20 cm in diameter, and very large (i.e., giant CMN) are over 50 cm in diameter. Rational for the size-based classification is that there is an increased risk of developing melanoma, a larger cosmetic impact and a greater surgical complexity with increasing size of CMN. In addition, large and giant CMN are often intermixed with various other neural crest-derived elements such as neural tissue and may be associated with extra-cutaneous malformations such as neurocutaneous melanocytosis, dandy-walker malformation, and vascular anomalies [1].

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PB - Springer Berlin Heidelberg

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In vivo confocal reflectance microscopy of congenital melanocytic nevi

Abstract

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