Incompatibility of oxalate desensitizers with acidic, fluoride-containing total-etch adhesives

C. K Y Yiu, N. M. King, B. I. Suh, L. J. Sharp, R. M. Carvalho, D. H. Pashley, F. R. Tay

Research output: Contribution to journalArticlepeer-review

38 Scopus citations


The use of oxalate desensitizers on acid-etched dentin prior to adhesive application can result in subsurface tubular occlusion by calcium oxalate crystals. However, the solubility of calcium oxalate increases in acidic solution. We hypothesized that total-etch adhesives can, depending upon their pH, interact with oxalate-desensitizer-treated dentin in an adverse manner. Acid-etched human dentin treated with 2 oxalate desensitizers (BisBlock and Super Seal) was bonded with 4 simplified total-etch adhesives: One-Step (OS), Single Bond (SB), OptiBond Solo Plus (OB), and Prime&Bond NT (PB). Composite-dentin beams were examined by SEM and TEM, both of which revealed numerous spherical globules on OB- and PB-bonded, desensitizer-treated dentin, but not in OS or SB samples. Bond strengths produced by OB and PB were significantly lower in oxalate-treated specimens than those produced by OS or SB. These surface globules may have interfered with hybridization of demineralized dentin with OB and PB resins and caused compromised bond strengths.

Original languageEnglish (US)
Pages (from-to)730-735
Number of pages6
JournalJournal of Dental Research
Issue number8
StatePublished - Aug 1 2005


  • Acid-etch
  • Fluoride
  • Oxalate desensitizer
  • pH
  • Single-bottle adhesives

ASJC Scopus subject areas

  • Dentistry(all)


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