Infection due to non-candidal yeasts

Invasive fungal infections have become an important cause of morbidity and mortality over the past two decades. More recently, uncommon fungi have been reported more frequently. The increased frequency may be due to an improved identification and reporting system, or an increase in the number of severely immunocompromised hosts. Diagnosing infections due to these rare or uncommon yeasts are a challenge, since the majority of the time we rely on traditional microbiologic assays and not improved diagnostic assays. In addition, the management of these types of fungal infections is difficult because of the lack of data, specifically, the lack of adequate in vitro susceptibility studies, and the paucity of any clinical treatment trials.