@article{27b38a9d6f3d4fdc9d09ef64282c3134,
title = "Initial presentation of granulomatosis with polyangiitis as urethral mass mimicking urethral cancer: A case report",
abstract = "Granulomatosis with polyangiitis (GPA) is a type of vasculitis in which granulomas deposit in small and medium-size vessels causing inflammation. It frequently affects the respiratory tract, both upper and lower tracts. Glomerulonephritis commonly occurs as well, and other systems can be affected such as the integumentary system and peripheral nervous system. Rarely, urogenital signs and symptoms are present. This report describes a case of a 19-year-old woman who presented with lower urinary tract symptoms and a urethral mass and was subsequently diagnosed with GPA. She responded well to treatment with corticosteroids, rituximab, and avacopan. This case highlights the importance of considering alternative diagnoses when a young woman presents with refractory urinary symptoms. It also highlights fertility issues relative to treatment of GPA that are of interest to the practicing obstetrician/gynecologist.",
keywords = "Granulomatosis with polyangiitis, Inflammation, Urethral mass",
author = "Namita Mohanty and Thinn San and Stephen Bell and Rasmita Jalla and James Williams and Isaac Fordjour and Naomi Siddiquee and Larisa Gavrilova-Jordan and Laura Carbone and Rachel Elam",
note = "Funding Information: Namita Mohanty contributed to analysis and interpretation of data and drafting the article. Thinn San contributed to analysis and interpretation of data and drafting the article. Stephen Bell contributed to analysis and interpretation of data and drafting the article. Rasmita Jalla contributed to analysis and interpretation of data and drafting the article. James Williams contributed to analysis and interpretation of data and drafting the article. Isaac Fordjour contributed to analysis and interpretation of data and drafting the article. Naomi Siddiquee contributed to analysis and interpretation of data and drafting the article. Larisa Gavrilova-Jordan contributed to patient care, analysis and interpretation of data and revising the article critically for important intellectual content. Laura Carbone contributed to analysis and interpretation of data and revising the article critically for important intellectual content. Rachel Elam contributed to patient care, analysis and interpretation of data and revising the article critically for important intellectual content. All authors approved the final manuscript. The authors received no funding from an external source for this case report. Written informed consent to publish this case was obtained from the patient. This article was not commissioned and was peer reviewed. Publisher Copyright: {\textcopyright} 2023",
year = "2023",
month = mar,
doi = "10.1016/j.crwh.2023.e00498",
language = "English (US)",
volume = "37",
journal = "Case Reports in Women's Health",
issn = "2214-9112",
publisher = "Elsevier BV",
}
