Introduction to sigma receptors: Their role in disease and as therapeutic targets

Sylvia B. Smith

doi:10.1007/978-3-319-50174-1_1

Introduction to sigma receptors: Their role in disease and as therapeutic targets

Sylvia B. Smith

Cellular Biology and Anatomy

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

This book highlights contributions from leaders in the field of sigma receptor research. Sigma receptors represent a promising, novel target for the treatment of neurodegenerative diseases, retinal degenerations, pain and substance abuse. Information is presented about tracers for molecular imaging these receptors, the newly determined crystal structure of human sigma 1 receptor and information about sigma 2 receptor. New discoveries about the role of sigma 1 receptors in cancer, pain, neuropsychiatric disorders, learning and memory, neuronal networks and depression are described. The compendium offers important insights about the direction unfolding for this exciting field of research.

Original language	English (US)
Pages (from-to)	1-4
Number of pages	4
Journal	Advances in experimental medicine and biology
Volume	964
DOIs	https://doi.org/10.1007/978-3-319-50174-1_1
State	Published - 2017

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Alcoholism
Amyotrophic lateral sclerosis
Crystal structure sigma receptor
Drug addiction
Neuronal degeneration
Neuroprotection
Pain
Retinal degeneration
Sigma receptor
Substance abuse
Therapeutic target

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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10.1007/978-3-319-50174-1_1

Cite this

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abstract = "This book highlights contributions from leaders in the field of sigma receptor research. Sigma receptors represent a promising, novel target for the treatment of neurodegenerative diseases, retinal degenerations, pain and substance abuse. Information is presented about tracers for molecular imaging these receptors, the newly determined crystal structure of human sigma 1 receptor and information about sigma 2 receptor. New discoveries about the role of sigma 1 receptors in cancer, pain, neuropsychiatric disorders, learning and memory, neuronal networks and depression are described. The compendium offers important insights about the direction unfolding for this exciting field of research.",

keywords = "Alcoholism, Amyotrophic lateral sclerosis, Crystal structure sigma receptor, Drug addiction, Neuronal degeneration, Neuroprotection, Pain, Retinal degeneration, Sigma receptor, Substance abuse, Therapeutic target",

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AB - This book highlights contributions from leaders in the field of sigma receptor research. Sigma receptors represent a promising, novel target for the treatment of neurodegenerative diseases, retinal degenerations, pain and substance abuse. Information is presented about tracers for molecular imaging these receptors, the newly determined crystal structure of human sigma 1 receptor and information about sigma 2 receptor. New discoveries about the role of sigma 1 receptors in cancer, pain, neuropsychiatric disorders, learning and memory, neuronal networks and depression are described. The compendium offers important insights about the direction unfolding for this exciting field of research.

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KW - Amyotrophic lateral sclerosis

KW - Crystal structure sigma receptor

KW - Drug addiction

KW - Neuronal degeneration

KW - Neuroprotection

KW - Pain

KW - Retinal degeneration

KW - Sigma receptor

KW - Substance abuse

KW - Therapeutic target

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SN - 0065-2598

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JO - Advances in experimental medicine and biology

JF - Advances in experimental medicine and biology

ER -

Introduction to sigma receptors: Their role in disease and as therapeutic targets

Abstract

UN SDGs

Keywords

ASJC Scopus subject areas

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