Abstract
Phosphorylation of α-synuclein protein at serine-129 (Ser129P) is a widely used marker for disease pathology in neurodegenerative disorders termed synucleinopathies. In groundbreaking work by Parra-Rivas, Madhivanan et al., Ser129P was shown to facilitate the normal function of α-synuclein, bearing significant implications for the transition from a physiological to pathological state.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 382-383 |
| Number of pages | 2 |
| Journal | Trends in Biochemical Sciences |
| Volume | 49 |
| Issue number | 5 |
| DOIs | |
| State | Published - May 2024 |
Keywords
- neuronal activity
- phosphorylation
- serine-129
- α-synuclein
ASJC Scopus subject areas
- Biochemistry
- Molecular Biology
Fingerprint
Dive into the research topics of 'Keeping neuronal activity in check: a novel role for α-synuclein serine-129 phosphorylation in the healthy brain'. Together they form a unique fingerprint.Cite this
- APA
- Standard
- Harvard
- Vancouver
- Author
- BIBTEX
- RIS