Kynurenine, a Tryptophan Metabolite That Increases with Age, Induces Muscle Atrophy and Lipid Peroxidation

Keyphrases

• Lipid Peroxidation 100%
• Kynurenine 100%
• Tryptophan Metabolites 100%
• Muscle Atrophy 100%
• Muscle Lipid 100%
• Aryl Hydrocarbon Receptor 45%
• Reactive Oxygen Species 36%
• Aged Mice 18%
• Indoleamine 2,3-dioxygenase 1 (IDO1) 18%
• Muscle Fiber Size 18%
• Muscle Strength 18%
• Sarcopenia 18%
• Neurodegeneration 9%
• Aging 9%
• Gene Expression 9%
• Molecular Mechanism 9%
• Protein Analysis 9%
• Array Data 9%
• Protein Synthesis 9%
• Novel Therapeutics 9%
• Cellular Mechanisms 9%
• Receptor Activation 9%
• Ubiquitin Ligase 9%
• Indoleamine 2,3-dioxygenase Inhibitor 9%
• Inhibitor-1 9%
• Bone Loss 9%
• Size Reduction 9%
• Muscle Size 9%
• Age-associated 9%
• Small Molecule Inhibitors 9%
• Muscle Mass Loss 9%
• Receptor Knockout 9%
• PCR Array 9%
• 1-methyl-D-tryptophan 9%
• Circulating Factors 9%
• Mouse Myoblasts 9%
• Very Long-chain acyl-CoA Dehydrogenase 9%
• Fibre muscle 9%
• Human Myoblasts 9%
• Muscle Loss 9%
• Heterochronic Parabiosis 9%

Biochemistry, Genetics and Molecular Biology

• Lipid Peroxidation 100%
• Tryptophan Metabolism 100%
• Kynurenine 100%
• Aryl Hydrocarbon Receptor 45%
• Mouse 27%
• Indoleamine 2,3-dioxygenase 27%
• Enzyme 9%
• Gene Expression 9%
• Polymerase Chain Reaction 9%
• Protein Characterization 9%
• Ubiquitin Ligase 9%
• Acyl-CoA 9%
• Tryptophan 9%
• Osteolysis 9%
• Protein Biosynthesis 9%
• Small Molecule 9%
• Parabiosis 9%
• Muscle Strength 9%
• Very-Long-Chain Acyl-CoA Dehydrogenase 9%

Pharmacology, Toxicology and Pharmaceutical Science

• Kynurenine 100%
• Tryptophan 100%
• Muscle Atrophy 100%
• Aromatic Hydrocarbon Receptor 45%
• Reactive Oxygen Metabolite 36%
• Mouse 27%
• Indoleamine 2,3 Dioxygenase 18%
• Sarcopenia 18%
• Protein Characterization 9%
• Ubiquitin Protein Ligase 9%
• Nerve Degeneration 9%
• Indoleamine 2,3 Dioxygenase Inhibitor 9%
• Long Chain Acyl Coenzyme A Dehydrogenase 9%