TY - JOUR
T1 - Large granular lymphocytic leukemia presenting late after solid organ transplantation
T2 - A case series of four patients and review of the literature
AU - Kataria, A.
AU - Cohen, E.
AU - Saad, E.
AU - Atallah, E.
AU - Bresnahan, B.
PY - 2014
Y1 - 2014
N2 - Post-transplantation lymphoproliferative disorder (PTLD) is a significant complication of solid organ transplantation. Most PTLD is of the B-cell subtype, although T-cell subtype PTLD uncommonly occurs. T-cell PTLDs are usually aggressive neoplasms and shorten patient and allograft survivals significantly. We present a single-center case series of 4 patients who developed T-cell large granular lymphocytic (LGL) leukemia, a rare T-cell PTLD characterized by large granular lymphocytes that have characteristic azurophilic granules and a highly variable clinical course.
AB - Post-transplantation lymphoproliferative disorder (PTLD) is a significant complication of solid organ transplantation. Most PTLD is of the B-cell subtype, although T-cell subtype PTLD uncommonly occurs. T-cell PTLDs are usually aggressive neoplasms and shorten patient and allograft survivals significantly. We present a single-center case series of 4 patients who developed T-cell large granular lymphocytic (LGL) leukemia, a rare T-cell PTLD characterized by large granular lymphocytes that have characteristic azurophilic granules and a highly variable clinical course.
UR - http://www.scopus.com/inward/record.url?scp=84926339267&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84926339267&partnerID=8YFLogxK
U2 - 10.1016/j.transproceed.2014.05.083
DO - 10.1016/j.transproceed.2014.05.083
M3 - Article
C2 - 25240311
AN - SCOPUS:84926339267
SN - 0041-1345
VL - 46
SP - 3278
EP - 3281
JO - Transplantation Proceedings
JF - Transplantation Proceedings
IS - 10
ER -