Large granular lymphocytic leukemia presenting late after solid organ transplantation: A case series of four patients and review of the literature

A. Kataria, E. Cohen, E. Saad, E. Atallah, B. Bresnahan

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Post-transplantation lymphoproliferative disorder (PTLD) is a significant complication of solid organ transplantation. Most PTLD is of the B-cell subtype, although T-cell subtype PTLD uncommonly occurs. T-cell PTLDs are usually aggressive neoplasms and shorten patient and allograft survivals significantly. We present a single-center case series of 4 patients who developed T-cell large granular lymphocytic (LGL) leukemia, a rare T-cell PTLD characterized by large granular lymphocytes that have characteristic azurophilic granules and a highly variable clinical course.

Original languageEnglish (US)
Pages (from-to)3278-3281
Number of pages4
JournalTransplantation Proceedings
Volume46
Issue number10
DOIs
StatePublished - 2014
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Transplantation

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