Abstract
N-Acyl threonine isopeptides undergo acyl transfer in chemical ligations via 5-, 8-, 9- and 10-membered cyclic transition states to yield natural peptides, representing the first examples of successful isopeptide ligations from N-acyl threonine units.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 9-18 |
| Number of pages | 10 |
| Journal | Arkivoc |
| Volume | 2015 |
| Issue number | 4 |
| DOIs | |
| State | Published - Sep 19 2014 |
Keywords
- Acylation
- Benzotriazole
- Chemical ligation
- Peptide
- Threonine
ASJC Scopus subject areas
- Organic Chemistry
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