Linking Hebb's coincidence-detection to memory formation

Joseph Zhuo Tsien

doi:10.1016/S0959-4388(00)00070-2

Linking Hebb's coincidence-detection to memory formation

Joseph Zhuo Tsien

Research output: Contribution to journal › Review article › peer-review

165 Scopus citations

Abstract

The theoretical foundations of learning and memory were laid by Donald Hebb 50 years ago. Recent genetic experiments that enhanced coincidence-detection of the NMDA receptor (a molecular master-switch in implementing Hebb's rule) and that led to better learning and memory in adult animals have substantially validated Hebb's rule in memory formation in the brain.

Original language	English (US)
Pages (from-to)	266-273
Number of pages	8
Journal	Current Opinion in Neurobiology
Volume	10
Issue number	2
DOIs	https://doi.org/10.1016/S0959-4388(00)00070-2
State	Published - Apr 1 2000
Externally published	Yes

ASJC Scopus subject areas

Neuroscience(all)

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10.1016/S0959-4388(00)00070-2

Cite this

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abstract = "The theoretical foundations of learning and memory were laid by Donald Hebb 50 years ago. Recent genetic experiments that enhanced coincidence-detection of the NMDA receptor (a molecular master-switch in implementing Hebb's rule) and that led to better learning and memory in adult animals have substantially validated Hebb's rule in memory formation in the brain.",

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AB - The theoretical foundations of learning and memory were laid by Donald Hebb 50 years ago. Recent genetic experiments that enhanced coincidence-detection of the NMDA receptor (a molecular master-switch in implementing Hebb's rule) and that led to better learning and memory in adult animals have substantially validated Hebb's rule in memory formation in the brain.

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Linking Hebb's coincidence-detection to memory formation

Abstract

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